Zolpidem

Products Zolpidem is commercially available as film-coated tablets, sustained-release tablets, and effervescent tablets (Stilnox, Stilnox CR, generics, USA: Ambien). It has been approved in many countries since 1990. Structure and properties Zolpidem (C19H21N3O, Mr = 307.39 g/mol) is an imidazopyridine that is structurally distinct from the benzodiazepines. It is present in drugs as zolpidem tartrate, … Zolpidem

Zopiclone

Products Zopiclone is commercially available in tablet form (Imovane, auto-generics). It has been approved in many countries since 1993. In the United States, the pure -enantiomer eszopiclone is also available (Lunesta). Structure and properties Zopiclone (C17H17ClN6O3, Mr = 388.8 g/mol) is a racemate and belongs to the cyclopyrrolones. It exists as a white to slightly … Zopiclone

Narcotics Effects and Side Effects

Products The narcotics are a group of centrally acting drugs and substances, which are strongly regulated and controlled by the state respectively by the drug and health authorities. This is primarily to prevent abuse and to protect the population from the undesirable effects and addiction. Certain narcotics – for example, many potent hallucinogens – are … Narcotics Effects and Side Effects

Anxiolytics

Products Anxiolytics are commercially available in the form of tablets, capsules, and injectable preparations, among others. Structure and properties Anxiolytics are a structurally heterogeneous group. However, the representatives can be divided into different classes. These include, for example, the benzodiazepines or the tricyclic antidepressants. Effects Anxiolytics have antianxiety (anxiolytic) properties. They usually have additional effects, … Anxiolytics

Orexin Receptor Antagonists

Products Orexin receptor antagonists are commercially available in tablet form. The first agent in this group to be approved in the United States was suvorexant (Belsomra) in 2014. Lemborexant (Dayvigo) followed in 2019. Structure and properties Orexin receptor antagonists are characterized by a central ring structure to which heterocycles are attached on both sides. Effects … Orexin Receptor Antagonists

Sleeping Pills: Effects, Side Effects, Dosage and Uses

Products Sleeping pills are most commonly taken in the form of tablets (“sleeping pills“). In addition, melting tablets, injectables, drops, teas and tinctures are also available, among others. The technical term hypnotics is derived from Hypnos, the Greek god of sleep. Structure and properties Within the sleeping pills, groups can be identified which have a … Sleeping Pills: Effects, Side Effects, Dosage and Uses

Eszopiclone

Products Eszopiclone is commercially available in the United States in the form of film-coated tablets (Lunesta). The drug is not registered in many countries. In contrast, the racemate zopiclone (Imovane) is on the market. Structure and properties Eszopiclone (C17H17ClN6O3, Mr = 388.8 g/mol) is the -enantiomer of zopiclone. It belongs to the cyclopyrrolones. Eszopiclone exists … Eszopiclone

Z-Drugs

Products Z-drugs – they are also called Z-substances – are usually taken in the form of film-coated tablets. In addition, other dosage forms such as sustained-release tablets and effervescent tablets are commercially available. Zolpidem (Stilnox) was the first substance from this group to be approved in many countries in 1990. In the literature, alluding to … Z-Drugs

Zaleplon

Products Zaleplon was commercially available in capsule form (Sonata, 5 mg, 10 mg). It was approved in many countries in 1999. It was discontinued from distribution in April 2013. Structure and properties Zaleplon (C17H15N5O, Mr = 305.3 g/mol) is a pyrazolopyrimidine and exists as a white powder that is practically insoluble in water. It is … Zaleplon

Jet Lag

Symptoms Possible symptoms of jet lag include: Sleep disturbances: drowsiness and fatigue during the day, insomnia at night. Digestive disorders Malaise, feeling sick Irritability, emotional upsets Concentration disorders Causes The cause of jet lag is a desynchronization of the sleep-wake rhythm during rapid travel across multiple time zones, typically by airplane. The time at the … Jet Lag

Psychotropic Drugs: Types, Effects, Indications, Dosage

Products Psychotropic drugs are commercially available, for example, in the form of tablets, melting tablets, dragées, capsules, drops, solutions and as injectables. The first psychotropic drugs were developed in the 1950s. Structure and properties Psychotropic drugs vary chemically, but groups with a common structure can be identified, for example, the benzodiazepines, the phenothiazines, and the … Psychotropic Drugs: Types, Effects, Indications, Dosage

Medication Overuse

Definition Medication overuse involves using self-purchased or physician-prescribed medications for too long, too much, or too frequently. The duration of therapy prescribed by a healthcare professional or by the professional and patient information is exceeded, the maximum single or daily dose is too high because of a dose increase, or the dosing interval is too … Medication Overuse