Metolazone

Products Metolazone is commercially available in tablet form as a generic product (Metolazone Galepharm). The original Zaroxolyn is no longer available. Structure and properties Metolazone (C16H16ClN3O3S, Mr = 365.8 g/mol) is a quinazoline sulfonamide that is sparingly soluble in water. It is structurally related to the thiazides. Effects Metolazone (ATC C03BA08) has diuretic and thiazide-like … Metolazone

Market Withdrawal of Drugs

Why is the distribution of medicines discontinued? Drugs are subject to a product life cycle. They are discovered, patented, developed, approved, marketed and, in some circumstances, withdrawn from the market years to decades later. Often, distribution is discontinued due to commercial considerations. For example, the cost of approval and production exceeds the revenue from sales. … Market Withdrawal of Drugs