Trigeminal Neuralgia: Causes and Treatment

Symptoms

  • Flashing, stabbing, sharp, short-lasting pain in the cheek, lips, chin, and lower jaw
  • Muscle spasms (“tic douloureux”).
  • Hypersensitivity to touch
  • Weight loss: chewing causes pain, patients stop eating
  • Usually unilateral, very rarely bilateral.

Trigger:

  • Touching, washing, shaving, smoking, talking, brushing teeth, eating and the like.
  • Trigger zones: Small areas in the nasolabial fold on the chin can trigger the pain.
  • Often also spontaneous

Causes

Classic trigeminal neuralgia: idiopathic, possibly due to demyelination of the nerve Symptomatic trigeminal neuralgia: secondary as a result of an underlying disease, eg, multiple sclerosis, neuritis, tumors, gout, depression, stress medical clarification (eg, MRI).

Risk factors

  • Female gender
  • Age
  • Multiple sclerosis
  • Hypertension

Non-drug treatment

Drug treatment

Antiepileptic drugs:

Neuroleptics Opioids ?

  • Treatment of the underlying disease in symptomatic trigeminal neuralgia.

Over-the-counter (OTC) trials:

  • Capsaicin was tested in an open study (Epstein, Marcoe, 1994 Pubmed) and can be applied topically as an ointment. It should not get into the eyes (see under capsaicin)!
  • NSAIDs are often ineffective