In many cases, endometrial cancer (cancer of the uterus) does not cause any symptoms and is therefore often discovered by chance. However, the following symptoms and complaints may indicate endometrial cancer:
Leading symptoms
- Vaginal bleeding (bleeding from the vagina).
- Nine out of ten women with endometrial cancer had previous postmenopausal bleeding (postmenopausal bleeding; bleeding after menopause)
- Menorrhagia – prolonged (> 6 days and increased menstrual bleeding.
- Metrorrhagia – vaginal bleeding occurring outside of menstruation (menstruation).
- Uterine fluorine – vaginal discharge originating in the uterus; may occur in advanced endometrial cancer.
- Abdominal pain – this may occur with advanced endometrial cancer.
Other indications
- Nine out of ten women with endometrial cancer had prior postmenopausal bleeding (prevalence of 90% (95% confidence interval: 84%-94%), but only 9% of women with postmenopausal bleeding have cancer (95% confidence interval: 8%-11%), corresponding to positive predictive value (PPV):Among women who had a minimum endometrial thickness of 4-5 mm documented sonographically, there was a pooled cancer risk of 19% (95% confidence interval: 14%-25%)
