The following are the most important diseases or complications that may be contributed to by hypercalcemia:
Cardiovascular system (I00-I99).
- Cardiac arrhythmias (arrhythmia, bradycardia (heartbeat too slow: < 60 beats per minute)).
- Hypertension (high blood pressure)
- Valve calcifications
Liver, gallbladder and bile ducts – Pancreas (pancreas) (K70-K77; K80-K87).
- Pancreatitis (inflammation of the pancreas).
Mouth, esophagus (esophagus), stomach, and intestines (K00-K67; K90-K93).
- Constipation (constipation)
Musculoskeletal system and connective tissue (M00-M99).
- Arthralgia (joint pain)
- Bone pain
- Myalgia (muscle pain)
Psyche – nervous system (F00-F99; G00-G99)
- Fatigue
- Muscle weakness
- Lethargy
- Confusion
- Depression
- Reflex attenuation
- Somnolence (drowsiness with abnormal sleepiness while maintaining responsiveness and arousal).
- Coma
- Brain Organic Psychosyndrome (HOPS)
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).
- Anorexia (loss of appetite).
- Nausea (nausea)/emesis (vomiting)
- Polydipsia (excessive thirst)
- Polyuria (increased urine output: > 1.5-3 l/day).
Genitourinary system (kidneys, urinary tract – reproductive organs) (N00-N99).
- Nephrolithiasis (kidney stones).
- Nephrocalcinosis (deposition of calcium salts in the renal vessels and connective tissues of the kidney).
- Renal insufficiency (kidney weakness)
Further
- Decrease in performance
- Cave: digitalis (→ calcium content increases intracellularly).