Acute Confusion: Test and Diagnosis

1st order laboratory parameters – obligatory laboratory tests.

Laboratory parameters 2nd order – depending on the results of the history, physical examination, etc. – for differential diagnostic clarification.

  • Differential blood picture
  • Blood gas analysis (ABG)
  • Thyroid parameters – TSH, fT3, fT4
  • Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin.
  • Renal parameters – urea, creatinine, cystatin C or creatinine clearance, if necessary.
  • Cardiac enzymescreatine kinase (CK), CK-MB (myocardial type of CK), lactate dehydrogenase (LDH) (LDH); troponin T (TnT) – Highly specific is the detection of elevated troponin T and troponin I in blood serum, as these rise early after infarction. These are commercially available as rapid tests, so many hospitals use them as routine markers for infarct diagnosis.
  • D-dimers (end product of proteolysis of fibrin) – for suspected pulmonary embolism (see also under pulmonary embolism/physical examination Wells score to determine the clinical probability of pulmonary embolism).
  • Alcohol level
  • Digoxin level
  • Drug screening
  • Toxicological examinations – in case of suspected intoxications.