Contraindications | Tegretal®

Contraindications

Tegretal® must not be taken if

  • A delayed transmission of excitation to the heart takes place (AV block),
  • There is damage to the bone marrow,
  • A metabolic disease such as acute porphyria is known or
  • So-called monoaminooxidase inhibitors can be taken to treat depression.

Interactions

Tegretal® is broken down by enzymes in the liver, which are also necessary for the breakdown of alcohol. Therefore, taking the drug leads to intolerance of even small amounts of alcohol. Grapefruit juice increases the amount of the active ingredient in the blood, which can lead to increased side effects. Therefore, both alcohol and grapefruit juice should be avoided during treatment with Tegretal®. Tegretal® influences many other drugs and leads to the ineffectiveness of the contraceptive pill, among other things.

Tegretal® during pregnancy

The use of Tegretal® during pregnancy is not recommended and should only be taken in consultation with a physician when therapy is absolutely necessary. The active ingredient can cause severe malformations, especially in the phase between the 20th and 40th day after fertilization, which is why the lowest possible dose is recommended during this period.Breastfeeding during treatment is possible, but the baby should be well supervised as the active ingredient also passes into the breast milk.