Pathogenesis (disease development)
Hand-foot-and-mouth disease (HFMD) is predominantly caused by group A enteroviruses (EV-A).
Enteroviruses are small, nonenveloped RNA viruses that belong to the Picornaviridae family.Group A enteroviruses (EV-A) include coxsackie A viruses (A2-A8, A10, A12, A14, A16), enterovirus A71 (EV-A71), and newer serotypes.
Coxsackie A16 viruses and coxsackievirus A6 and A10 are the most common cause of HFMK.
Etiology (Causes)
- Contact with individuals with HFMK
