The following are the most important diseases or complications that may be contributed to by hand-foot-and-mouth disease (HFMD):
Skin and subcutaneous (L00-L99).
- Onycholysis (partial detachment of the nail plate from the nail bed) or onychomadesis (complete detachment of the nail plate from the nail bed) – in atypical courses: Loss of fingernails and toenails (usually within four weeks after infection).
Psyche – nervous system (F00-F99; G00-G99).
- Encephalitis (inflammation of the brain), aseptic (very rare).
- Meningitis (meningitis), aseptic (very rare).
- Paresis (paralysis), polio-like.
