The following are the most important diseases or complications that may be contributed to by Hashimoto’s thyroiditis:
Respiratory system (J00-J99)
- Pleural effusion – accumulation of water in the lung/lung pleural space.
Endocrine, nutritional, and metabolic diseases (E00-E90).
- Hypothyroidism (underactive thyroid; manifest or latent); rate of progression from latent to definite hypothyroidism
- Myxedema – pasty (puffy; bloated) skin showing nonpushable, doughy edema (swelling) that is not positional; facial and peripheral; occurring primarily on the lower legs
Skin and subcutaneous (L00-L99).
- Alopecia (diffuse hair loss)
Cardiovascular system (I00-I99)
- Apoplexy (stroke; risk increase especially in the first year after diagnosis of autoimmune thyroiditis).
- Arterial hypertension (high blood pressure).
- Coronary artery disease (CAD; coronary artery disease).
- Pericardial effusion (pericardial effusion)
Neoplasms – tumor diseases (C00-D48)
- Thyroid carcinoma
Ears – mastoid process (H60-H95)
- Hearing loss
Psyche – nervous system (F00-F99; G00-G99)
- Anxiety disorders
- Dementia
- Depression
- Hashimoto’s encephalopathy – changes in the brain likely related to Hashimoto’s thyroiditis.
- Carpal tunnel syndrome – compression syndrome of the median nerve in the region of the carpus.
- Concentration disorders
- Paresthesias (insensations)
- Psychosis
- Cerebellar ataxia (gait disorder)
Symptoms and abnormal clinical and laboratory parameters, not elsewhere classified (R00-R99).
- Muscle spasms
- Muscle pain
- Muscle stiffness
Genitourinary system (kidneys, urinary tract – sex organs) (N00-N99)
- Menorrhagia – menstruation is prolonged (> 6 days) and increased.
- Oligomenorrhea (the interval between periods is > 35 days and ≤ 90 days, i.e., periods occur too infrequently); secondary amenorrhea (no menstrual bleeding for > 90 days)