Rosacea

Rosacea: Drug Therapy

Therapy target Complete freedom from appearance Therapy recommendations General measures: Avoidance of irritants and triggering factors. Local therapy (“topical”; topical therapy). Approved therapy: Rosacea papulopustulosa (rosacea associated with papules/vesicles and pustules/pustules): metronidazole (nitroimidazoles), azelaic acid (acne therapeutics). Erythematous (“associated with skin redness”) rosacea: brimonidine (alpha-2-adrenergic receptor agonist). Off-label use (use outside the indications or group … Rosacea: Drug Therapy

Rosacea: Surgical Therapy

In rhinophyma (“bulbous nose“; reddened, bulbous thickening of the tip of the nose), surgical correction (by dermabrasion, i.e., abrading superficial areas of skin with a rotating abrasive head or by scalpel) can be performed.

Rosacea: Prevention

To prevent rosacea, attention must be paid to reducing individual risk factors. Behavioral risk factors Diet Hot drinks Strongly spiced food/spices (e.g. chili). Pleasure food consumption Alcohol Physical activity Sports Body care Use of skin irritants such as soap, peeling agents, and harsh or alcohol-based face creams (cosmetics). Hot baths / heat during saunas Sunbathing … Rosacea: Prevention

Rosacea: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate rosacea: Erythema (redness of the skin) occurs initially; this is usually in the center of the face, but rarely also on the décolleté Later, telangiectasias (vascular dilatation; couperosis) and papules (no comedones!) or pustules may appear Still later, diffuse connective tissue and sebaceous gland hyperplasias and phyma (tuberous … Rosacea: Symptoms, Complaints, Signs

Rosacea: Causes

Pathogenesis (disease development) The exact pathomechanism of rosacea is unclear. Etiology (Causes) The following factors may be associated with rosacea: Biographic causes Genetic exposure to parents, grandparents. Genes/SNPs (single nucleotide polymorphism; Engl:) SNP: rs763035 in an intergenic region. Allele constellation: CT (1.2-fold). Allele constellation: TT (1.4-fold) Skin type – fair-skinned people (skin type I-II). Behavioral … Rosacea: Causes

Rosacea: Therapy

General measures Avoidance Skin irritating substances such as soap or peeling agents! Sharp or alcohol-containing face creams Preparations containing camphor, menthol (monocyclic monoterpene alcohol), sodium lauryl sulfate. Use soap-free detergents Low fat face / sun creams Do not bathe too hot! UVA / UVB protection (when sunbathing) In rosacea ophthalmica (often with blepharoconjunctivitis/inflammation of the … Rosacea: Therapy

Rosacea: Secondary Diseases

The following are the most important diseases or complications that can be caused by rosacea: Eyes and eye appendages (H00-H59). Blepharitis* (inflammation of the eyelids). Hailstones (chalazia) Keratitis* (corneal inflammation) with infiltration, ulceration (ulceration), vascularization and scarring. Conjunctivitis (conjunctivitis) (conjunctival hyperemia). * Appearance of rosacea ophthalmica (ophthalmorosacea) in approximately 30-50% of patients. Skin and subcutaneous … Rosacea: Secondary Diseases

Rosacea: Classification

Stages of rosacea Stage Designation Description 0 Preliminary stage of rosacea Seizure-like, transient erythema (extensive reddening of the skin) I erythematous-teleangiectatic Rosacea erythematosa Characterized by erythema and telangiectasias (vasodilatation); additional burning, stinging, and pruritus (itching) II papulopustular Rosacea papulopustulosa Additionally appearing papules (vesicles; no comedones!) and pustules (painful pustules) II glandular-hyperplastic glandular-hyperplastic rosacea Associated with … Rosacea: Classification

Rosacea: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; furthermore: Inspection (viewing) of the skin [initially appearing erythema (skin redness) (center of face, rarely décolleté); later telangiectasias (vascular dilatation; couperosis), papules or pustules; still later growths of connective tissue and sebaceous … Rosacea: Examination

Rosacea: Medical History

Medical history (history of the patient) represents an important component in the diagnosis of rosacea. Family history Is there a history of skin disease in your family? Social history What is your profession? Current medical history/systemic history (somatic and psychological complaints). Have you noticed any redness of the skin? If so, where are these localized? … Rosacea: Medical History

Rosacea: Or something else? Differential Diagnosis

Respiratory System (J00-J99) Unspecified paranasal sinus disease. Blood, hematopoietic organs – immune system (D50-D90). Sarcoidosis (synonyms: Boeck’s disease; Schaumann-Besnier’s disease) – systemic disease of connective tissue with granuloma formation. Skin and subcutaneous (L00-L99). Acne (here: Acne papulopustulosa) (DD due toRosacea papulopustulosa). Bromoderm – drug reaction to bromine preparations. Gianotti-Crosti syndrome (synonyms: Acrodermatitis papulosa eruptiva infantilis, … Rosacea: Or something else? Differential Diagnosis