Acarbose Definition Glucobay® is an antidiabetic and is used for the treatment and comedication of diabetes mellitus type I and II. Mode of action Glucobay® inhibits an enzyme called α-glucosidase, which prevents the rise of blood sugar levels in the body after meals. α-Glucosidase has normally the task in the intestine the multiple sugars to … Glucobay
Contraindications Glucobay® also has certain contraindications for which the drug must not be taken. These include: A hypersensitivity reaction with previous use of Glucobay® Chronic inflammatory bowel disease (here the risk of a disturbance of absorption in the bowel may be too high) All types of diabetic metabolic derailment with coma ketoacidosis and hypoglycaemia Coma … Contraindications | Glucobay
Synonyms in a broader sense Diabetes drugs, diabetes mellitus, repaglinide (e.g. Novonorm®) and nateglinide (e.g. Starlix®) How do the glinides repaglinide (e.g. Novonorm®) and nateglinide (e.g. Starlix®) work? Repaglinide (Novonorm®) and nateglinide (Starlix®) promote the release of insulin from the pancreas. A prerequisite for this is that the pancreas itself can still produce insulin. When … Glinide
Side effects As with other oral antidiabetics, gastrointestinal problems such as nausea and vomiting as well as diarrhea or constipation can occur during therapy with repaglinide (Novonorm®) or nateglinide (Starlix®). 10 percent of patients treated with glinides experienced headaches and diffuse visual disturbances, which were attributed to strongly fluctuating blood glucose levels. Under therapy with … Side effects | Glinide
The PCO syndrome is an abbreviation for polycystic ovary syndrome. It is a metabolic disorder that affects women who are of a sexually mature age. It is very common and causes some sequelae, such as infertility or hyperandrogenism. The exact causes of the syndrome are still largely unknown, but it is suspected that it may … Metformin in polycystic ovary syndrome
Alcohol consumption and metformin When treating with metformin, it is recommended to avoid alcohol in any case, as the effect of alcohol can usually increase significantly. Often the effects of the drinks are felt much earlier – people affected can tolerate much less alcohol and are alcoholized much earlier and there is a risk of … Alcohol consumption and metformin | Metformin in polycystic ovary syndrome
Pregnancy and Metformin In connection with PCO, previous studies and observations have shown that the abortion rate was significantly reduced when pregnant women continued to take the drug metformin during the first trimester. On the other hand, there was a comparatively high rate of miscarriages if pregnant women were not treated with metformin or if … Pregnancy and Metformin | Metformin in polycystic ovary syndrome
Side effects of Metformin The side effects of metformin are unfortunately extensive. Combinations with other groups of active ingredients such as alcohol should also be considered. We have therefore published a completely separate page on the subject of “Side effects of metformin“. All articles in this series: Metformin in polycystic ovary syndrome Alcohol consumption and … Side effects of Metformin | Metformin in polycystic ovary syndrome
Insulin is an endogenous hormone produced in the pancreas. Insulin causes sugar to be absorbed from the blood into the liver and muscles. This causes the blood sugar level to drop. Insulin, also known as insulinum, insulin hormone or islet hormone, can be assigned to the class of proteohormones. All members of this hormone class … Insulin
Insulin Release Insulin is released by various stimuli initiated by the organism. Probably the most important stimulus for the release of the tissue hormone is an increase in the blood sugar level. From a glucose level of approximately 5 mmol/l, the beta cells of the pancreas begin to secrete insulin. In addition, various amino acids, … Insulin Release | Insulin
Insulin associated diseases The metabolic disease known as insulin resistance (synonym: pre-diabetes) is a preliminary stage of type 2 diabetes. It has now been proven that the causes of this disease have a strong genetic component. Studies have shown that 40% of children whose parents have type 2 diabetes suffer from insulin resistance. If two … Insulin associated diseases | Insulin
Indications When is insulin used for therapy? People with type 1 diabetes are dependent on externally supplied insulin because the body’s own insulin production and release is not sufficient. Type 2 diabetics are treated with insulin when dietary measures and oral medications (tablets) no longer have any effect and blood glucose control is unsatisfactory. In … Indications | Insulin
