Mode of operation Diabetes mellitus is a disease in which either no (type I) or too little (type 2) insulin is produced. Instead of being absorbed into the cells of the body, the sugar glucose increasingly accumulates in the blood. Actrapid mimics the effect of the body’s own insulin by binding to receptors in fat … Mode of operation | Actrapid®
What is insulin anyway? Insulin is a hormone produced by the pancreas and released into the blood. It is needed mainly by liver, muscle and fat cells to be able to absorb glucose, i.e. sugar, from the blood, which means that it is also responsible for lowering the blood sugar level. It thus serves to … Insulin delivery
Antagonist glucagon Unlike insulin, which lowers blood sugar levels, the hormone glucagon increases the amount of sugar in the blood. It is the direct counterpart to insulin. So glucagon is a catabolic hormone that breaks down and releases sugar from energy stores such as the liver. It also activates some enzymes that help break down … Antagonist glucagon | Insulin delivery
Trade name Among other things Glucobay®. Introduction Acarbose is used as a drug for the treatment of non-insulin-dependent diabetes mellitus (i.e. mainly type II diabetes). It works by inhibiting certain enzymes in the gastrointestinal tract (alpha-glucosidases) which are responsible for the breakdown of sugars (carbohydrates). This leads to a delay in the absorption of glucose. … Acarbose
Interactions Some medications can weaken the effect of acarbose. These include steroids (e.g. cortisone), the “pill” (oral contraceptives), medicines to treat epilepsy (antiepileptic drugs, such as phenytoin), certain drugs to treat high blood pressure or heart disease (calcium channel blockers), water tablets (diuretics), thyroid hormones (e.g. L-thyroxine), hormones (e.g. estrogen), certain tuberculosis drugs (isoniazid) and … Interactions | Acarbose
Glimepiride, antidiabetic, sulfonylureaAmaryl® is a so-called antidiabetic and is used to lower permanently high blood sugar levels. It should only be used when a suitable diet, additional exercise and weight loss are not sufficient to lower blood sugar levels adequately. Amaryl® contains the active ingredient glimepiride and is suitable exclusively for type 2 diabetics, as … Amaryl®
What are alpha-glucosidase inhibitors and how do they work? The active ingredients from the group of substances known as alpha-glucosidase inhibitors inhibit enzymes in the intestine that break down carbohydrates absorbed with food into glucose. As a result, blood sugar rises only slowly after eating. However, alpha-glucosidase inhibitors have no effect when consuming foods with … Alpha-glucosidase inhibitor
Contraindications If you already suffer from an intestinal disease such as Crohn’s disease, ulcerative colitis, alpha-glucosidase inhibitors should not be taken in order to avoid further strain on the intestinal structures. Since the increased gas formation in the intestine also increases the general pressure in the abdomen, alpha-glucosidase inhibitors should not be taken in the … Contraindications | Alpha-glucosidase inhibitor
Intake during pregnancy and lactation Pregnant women and nursing mothers are not advised to take alpha-glucosidase inhibitors. Children and adolescents under the age of 18 should also avoid them. Unfortunately, there is too little or hardly any experience available as to how alpha-glucosidase inhibitors affect the development of the human body. Furthermore, alpha-glucosidase inhibitors should … Intake during pregnancy and lactation | Alpha-glucosidase inhibitor
