Synonyms Drugs Diabetes mellitus, diabetes drugs, glibenclamide (e.g. Euglucon ®N), glimepiride (e.g. Amaryl®), gliquidone (e.g. Glurenorm®) How do sulfonylureas work? Sulfonylureas stimulate the pancreas to release more insulin. The prerequisite for this, however, is that the beta cells of the pancreas are still capable of producing insulin themselves. When the pancreas is no longer able … Read more

Dosage and dose adjustment | Sulfonylureas

Dosage and dose adjustment The recommended dosage is as follows: In the beginning, start with half a tablet in the morning. Start with one tablet in the morning. Start with 15 mg or half a tablet in the morning. Every three months your doctor will check whether the current dosage is having the desired blood … Read more

When should sulfonylureas not be taken ? | Sulfonylureas

When should sulfonylureas not be taken ? Sulfonylureas must not be taken in case of hypersensitivity to drugs of the sulfonamide type. These include antibiotics used for urinary tract infections (Cotrimoxazole). Some medicines for high blood pressure (diuretics) have a similar origin and have been discontinued by some people due to hypersensitivity. Your doctor will … Read more

SGLT 2 inhibitors

What are SGLT2 inhibitors? SGLT2 inhibitors, also called gliflozines, are drugs from the group of oral antidiabetics. They are therefore used to control blood sugar levels in diabetes mellitus. SGLT2 stands for a sugar transporter in the kidney. The transporter absorbs the sugar back into the bloodstream and the inhibition ensures that more sugar is … Read more

The side effects of SGLT2 inhibitor | SGLT 2 inhibitors

The side effects of SGLT2 inhibitor The most common side effect is severe hypoglycaemia, which occurs particularly often when insulin or other antidiabetics are also used. This affects more than 10 percent of all users and is thus one of the very frequent side effects. Genital infections and urinary tract infections occur frequently, i.e. in … Read more

The interactions with other substances | SGLT 2 inhibitors

The interactions with other substances SGLT2 inhibitors can increase the effect of diuretics, leading to dehydration and low blood pressure. Together with insulin or sulfonylureas, severe hypoglycemia can occur, which can also be life-threatening. Other interactions have been classified as clinically irrelevant. Concurrent use with metformin, digoxin, warfarin, sitagliptin, carbamazepine and many other medications is … Read more

Alternatives to SGLT2 inhibitors? | SGLT 2 inhibitors

Alternatives to SGLT2 inhibitors? There is a wide range of possible preparations in the treatment of diabetes mellitus type 2, the first group being the sulfonylureas, which cause an increase in insulin secretion. The second group are glinides, which also increase insulin secretion. The incretins also promote the release of insulin. Metformin acts directly on … Read more


The active ingredient of the drug Siofor® is called metformin and belongs to the group of oral antidiabetics. Siofor® is used in the treatment of diabetes mellitus type 2, formerly known as “adult-onset diabetes”. Today, type 2 diabetes mellitus can also occur at an earlier age. It is prescribed by a physician when dietary measures … Read more

Metabolization | Siofor®

Metabolization Siofor® is excreted unchanged via the kidney and thus in the urine. It is therefore important to have the laboratory values of the kidneys (here: especially the serum creatinine) determined on a regular basis in order to be able to adjust the dosage in good time if kidney function is impaired or to be … Read more


Synonyms in a broader sense Diabetes drugs, drugs Diabetes mellitus, Biguanide, Glucophage®, Mescorit®, Diabesin®, Siofor® How do biguanides act like metformin? According to current medical guidelines, metformin is used first when diabetes mellitus cannot be controlled well through exercise, sport and weight loss. Metformin has been on the market for decades and has proven to … Read more

When should you not take Metformin? | Metformin

When should you not take Metformin? Just to avoid the undesirable effects under a metformin intake, the following contraindications should be noted. If your kidneys are not working properly, metformin should not be taken. Especially diabetics often have limited kidney function. Your doctor will check your blood for a certain kidney value (creatinine) and thus … Read more

Metformin and alcohol | Metformin

Metformin and alcohol If you are taking metformin, the excessive consumption of alcohol carries a number of dangers that should be taken seriously. One particularly important point is that you will be alcoholized much faster than without taking the drug. It is very easy to overlook the point when it is enough with the alcohol … Read more