25-Hydroxy vitamin D (synonyms: calcifediol, 25-OH-D3, 25-OH vitamin D) is a vitamin that regulates calcium and phosphate balance. Regulation of calcium and phosphate balance: Intestine (calcium and phosphate absorption). Kidneys (calcium and phosphate reabsorption). Bones (mobilization of calcium and phosphate with the participation of parathyroid hormone and calcitonin). Coming from food intake, cholecalciferol is converted … 25-Hydroxy Vitamin D
Deoxypyridinoline (DPD; synonyms: pyridinium crosslinks; total crosslinks; crosslinks) is a very specific marker of bone resorption and thus of osteoclast (bone resorption cell) activity. Deoxypyridoline belongs to the group of pyridinolines that occur in serum during the splitting of collagen fibrils into so-called crosslinks. In addition to DPD, pyridinoline (PYD) also occurs, but it does … Deoxypyridinoline (DPD)
Bone phosphatase (also called ostase or bone AP (bone-specific alkaline phosphatase)) is an isoenzyme of alkaline phosphatase. Alkaline phosphatase consists of a group of isoenzymes (liver AP, the bile duct AP, and the small intestine AP) that accompany many different metabolic processes in the body. Bone phosphatase is the isoenzyme that has the highest bone … Bone Phosphatase
Collagen-I telopeptide is a marker of bone resorption and thus of osteoclast (bone resorption cell) activity. Collagen-I telopeptide is not bone-specific, as it is also found in other organs such as skin and cartilage. It is subject to wide diagnostic variations. Collagen I telopeptide is never the 1st choice laboratory parameter for the above reasons. … Collagen I Telopeptide
Osteocalcin (OC; synonyms: bone γ-carboxylglutamic acid-containing protein; bone Gla-protein (BGP)) is a peptide hormone. Osteocalcin is produced in bone by osteoblasts (bone-building cells) and in tooth by odontoblasts (dentin-forming cells) and binds to hydroxyapatite and calcium. The synthesis of osteocalcin is regulated by 1,25-dihydroxy vitamin D (synonyms: calcitriol, 1α-25-OH-D3). However, osteocalcin can only perform its … Osteocalcin
