Protein-S (protein S) is a protein (protein) from the blood clotting system that is produced in the liver. It is the cofactor of protein-C, which inhibits blood clotting factors V and VIII.Protein-S is vitamin K-dependent. Protein-S deficiency results in an increased risk of thrombosis. The procedure Material needed Citrate plasma Preparation of the patient Not … Protein-S
Prothrombin is a component of blood clotting. It is formed in the liver and converted by an activator into thrombin, which is relevant for blood clotting. Thrombin ensures that platelets are released and can form a wound closure (platelet aggregation).Furthermore, thrombin converts fibrinogen into fibrin, which is a component of a thrombus (blood clot). In … Factor II Mutation (Prothrombin Mutation)
Plasminogen activator inhibitors (synonyms: plasminogen activator inhibitors, PAIs) are the proteins in the blood that are involved in blood clotting. They act as inhibitors of fibrinolysis (fibrin cleavage; the body’s own dissolution of a blood clot). There are four types of plasminogen activator inhibitors, with type 1 being the most important. Plasminogen activator inhibitor type … Plasminogen Activator Inhibitor
Protein-C (protein C) is a protein (protein) from the blood clotting system that is produced in the liver. It inhibits factors V and VIII.Protein-C is vitamin K-dependent. A cofactor of protein-C is protein-S. Protein-C deficiency results in an increased risk of thrombosis. The procedure Material needed Citrate plasma Preparation of the patient Not necessary Disruptive … Protein-C
Activated protein-C is a protein (protein) from the blood clotting system. It is dependent on vitamin K. APC resistance (synonym: factor V Leiden mutation (FVL mutation); note: V stands for the number five) is a mutation in a blood clotting factor, factor V, making it resistant to protein-C. This results in an increased tendency to … APC Resistance
