Products Oritavancin was approved in the United States in 2014 as an infusion preparation (Orbactiv). The drug has not yet been registered in many countries. Structure and properties Oritavancin is present in drugs as oritavancin phosphate (C86H97N10O26Cl3 – 2H3PO4, Mr = 1989.1 g/mol) is present, a complex semisynthetically produced lipoglycopeptide structurally related to other glycopeptide … Oritavancin
Products Vancomycin is commercially available as an injectable and in capsule form (Vancocin, generics). It was discovered in 1957 in soil samples from a jungle in Borneo and has been approved in many countries since 1959. Structure and properties Vancomycin is present in drugs as vancomycin hydrochloride (C66H76Cl3N9O24, Mr = 1486 g/mol) is present, a … Vancomycin
Products Telavancin is commercially available as a powder for the preparation of a concentrate for infusion solution (Vibativ). It was approved in the EU in 2011. Structure and properties Telavancin (C80H106Cl2N11O27P, Mr = 1755.6 g/mol) is a complex molecule and a semisynthetic derivative of vancomycin. It was supplemented with, among other things, a lipophilic decylaminoethyl … Telavancin
Products Dalbavancin was approved in the United States and the EU in 2014 in the form of an infusion preparation (Dalvance, Xydalba). The drug has not yet been registered in many countries. Structure and properties Dalbavancin is a complex lipoglycopeptide semisynthetically derived from a fermentation product of -species. It exists as a mixture of structurally … Dalbavancin
Products Teicoplanin is commercially available as a drug for parenteral administration (Targocid, generics). It has been approved in many countries since 1990. Structure and properties Teicoplanin is a mixture of structurally similar and complex molecules isolated from. Effects Teicoplanin (ATC J01XA02) is mostly bactericidal and partially bacteriostatic against aerobic and anaerobic Gram-positive bacteria. The effects … Teicoplanin
