Metformin: Drug Effects, Side Effects, Dosage and Uses

Products Metformin is commercially available in many countries in the form of film-coated tablets and has been available since 1960. In addition to the original Glucophage, numerous generics are available today. Metformin is often combined with various other antidiabetic drugs fix. It has been used medically since 1957. Other antidiabetic biguanides such as phenformin and … Metformin: Drug Effects, Side Effects, Dosage and Uses

Phenformin

Products Phenformin has been off the market in many countries since the late 1970s because of the potential adverse effects. Structure and properties Phenformin (C10H15N5, Mr = 205.3 g/mol) is a biguanide with a similar structure to metformin. Phenformin was the first agent in this group of drugs. Effects Phenformin (ATC A10BA01) has antidiabetic and … Phenformin

Buformin

Products Buformin (Silubin retard, dragées) is no longer commercially available in many countries and many more because of the potential adverse effects. Structure and properties Buformin (C6H15N5, Mr = 157.2 g/mol) is a 1-butylbiguanide with a similar structure to metformin from the same drug group. It is present in drugs as buformin hydrochloride. Effects Buformin … Buformin