Monoaminooxidase B Inhibitors

Rasagiline

Products Rasagiline is commercially available in tablet form (Azilect). It has been approved in many countries since 2005. Generic versions were first released in 2015. Structure and properties Rasagiline (C12H13N, Mr = 171.24 g/mol) is an aminoindan derivative and has an asymmetric carbon atom. Therapeutic uses are found for the -enantiomer. It is present in … Rasagiline

Safinamide

Products Safinamide is commercially available in the form of film-coated tablets (Xadago). It was approved in many countries and in the EU in 2015 and in the US in 2017. Structure and properties Safinamide (C17H19FN2O2, Mr = 302.3 g/mol) is an α-aminoamide derivative. Effects Safinamide (ATC N04BD03) has indirect dopaminergic properties. It is a selective … Safinamide