Products Gestodene is marketed in many countries exclusively in combination with ethinyl estradiol in the form of dragées and film-coated tablets as an oral contraceptive (“pill”). It has been approved in many countries since 1986. Structure and properties Gestodene (C21H26O2, Mr = 310.4 g/mol) exists as a white to yellowish crystalline powder that is practically … Gestodene
Products Vaginal (contraceptive ring): NuvaRing (+ ethinyl estradiol) see under contraceptive ring. Implanted (plastic rods): Implanon Structure and properties Etonogestrel (3-keto-desogestrel, C22H28O2, Mr = 324.5 g/mol) is the biologically active metabolite of desogestrel (Cerazette), a progestin derived from 19-nortestosterone. Effects The contraceptive effects of etonogestrel (ATC G03AC08) are primarily due to inhibition of ovulation. Indications … Etonogestrel
Products Dienogest is commercially available for endometriosis therapy in tablet form (Visanne, generic). Structure and properties Dienogest (C20H25NO2, Mr = 311.4 g/mol) is a derivative of 19-nortestosterone (nandrolone) and carries a cyanomethyl group. Effects Dienogest (ATC G03DB08) has progestogenic and antiandrogenic properties. The effects are due to selective binding to progesterone receptors. Dienogest abolishes the … Dienogest (Endometriosis Therapy)
Products Nomegestrol acetate is commercially available as a fixed combination with the natural estrogen estradiol in the form of film-coated tablets (Zoely). It has been approved in many countries since 2012 and entered the market in 2013. Structure and properties Nomegestrol acetate (C23H30O4, Mr = 370.5 g/mol) is derived from progestin 19-norprogesterone and progesterone, respectively. … Nomegestrol Acetate
Products Progesterone gel Progestogel for the treatment of mastodynia has been approved in many countries since 1980. Structure and properties Progesterone (C21H30O2, Mr = 314.5 g/mol) exists as a white crystalline powder or as colorless crystals and is practically insoluble in water. It corresponds in structure and properties to the natural sex hormone. Effects Progesterone … Progesterone Gel
Products Dydrogesterone is commercially available in the form of film-coated tablets (Duphaston, fixed combination with estradiol: Femoston conti). It has been approved in many countries since 1963. Structure and properties Dydrogesterone (C21H28O2, Mr = 312.4 g/mol) Effects Dydrogesterone (ATC G03DB01) has gestagenic properties. Indications Hormone replacement therapy in combination with an estrogen (menopause, ovariectomy). Cycle … Dydrogesterone
Products Desogestrel is commercially available as a monopreparation in the form of film-coated tablets (Cerazette, 75 µg, generic). The active ingredient was approved in the 1980s. In 2014, generic versions were registered for the first time in many countries. Structure and properties Desogestrel (C22H30O, Mr = 310.5 g/mol) exists as a white crystalline powder that … Desogestrel: Drug Effects, Side Effects, Dosage and Uses
Products Norethisterone is commercially available in tablet form (Primolut N). It has been approved in many countries since 1959. Micronovum and Trinovum were withdrawn from the market in many countries in 2013. Structure and properties Norethisterone (C20H26O2, Mr = 298.4 g/mol) exists as a white to yellowish white crystalline powder that is practically insoluble in … Norethisterone
Structure and properties Norethisterone acetate (C22H28O3, Mr = 340.5 g/mol) exists as a white to yellowish white crystalline powder, which is practically insoluble in water. See also under norethisterone. Effects Norethisterone acetate (ATC G03AC01) has gestagenic properties. Indications Hormone replacement therapy
Products Norgestimate is commercially available in tablet form in combination with ethinyl estradiol (Cilest). It has been approved in many countries since 1986. Structure and properties Norgestimate (C23H31NO3, Mr = 369.5 g/mol) is a prodrug that is biotransformed in the body to the active metabolites norgestrel and norelgestromin (17-deacetyl norgestimate). Effects The combination (ATC G03AA11) … Norgestimat
