Products Ephedrine is commercially available in many countries in the form of injectable solutions, in combination cold remedies, and in veterinary medicines. Structure and properties Ephedrine (C10H15NO, Mr = 165.2 g/mol) is commonly present in drugs as ephedrine hydrochloride, a white crystalline powder or colorless crystals that are readily soluble in water. Other salts are … Ephedrine: Drug Effects, Side Effects, Dosage and Uses
Products Dopamine is commercially available as an infusion solution concentrate (Dopamine Sintetica). It has been approved in many countries since 1975. Structure and properties Dopamine (C8H11NO2, Mr = 153.2 g/mol) is an endogenous substance formed from DOPA by decarboxylation and can be oxidized to norepinephrine. Effects Dopamine (ATC C01CA04) has sympathomimetic and dopaminergic properties. Effects … Dopamine Neurotransmitter
Products Mirvaso brimonidine gel was approved in the EU in 2013 and in many countries in 2014. Structure and properties Brimonidine (C11H10BrN5, Mr = 292.1 g/mol) is present in the drug as brimonidine tartrate, a white to yellow powder that is soluble in water. It has a similar structure to clonidine and apraclonidine. Effects Brimonidine … Brimonidine Gel
Products Tetryzoline is commercially available in the form of eye drops (Visine Classic, combination products). It has been approved in many countries since 1959. The active ingredient is also known as tetrahydrozoline. Nasal sprays or [nasal drops containing tetryzoline are currently no longer available in many countries. Structure and properties Tetryzoline (C13H16N2, Mr = 200.3 … Tetryzoline: Drug Effects, Side Effects, Dosage and Uses
Products Phenylephrine is commercially available in the form of nasal drops, as a nasal spray, nasal gel, eye drops, oral powder, as an injectable, and in capsules as a mono- or combination preparation (e.g., Neo-Citran, Triofan Rhinitis Capsules, Vibrocil). It has been approved in many countries since 1968. Rhinopront is off the market. See also … Phenylephrine
Products Phenylephrine is commercially available in the form of eye drops (Neosynephrine-POS 5%). Structure and properties Phenylephrine(C9H13NO2, Mr = 167.2 g/mol) is a derivative of epinephrine. It exists as phenylephrine hydrochloride, a white crystalline powder that is readily soluble in water. The drug contains the pure -enantiomer. Effects Phenylephrine (ATC S01FB01) has mydriatic and vasoconstrictor … Phenylephrine Eye Drops
Products Phenylpropanolamine is no longer on the market as a human drug in many countries. It was formerly contained in Astho-Med Syrup, Contac, Dimetane, Dimetapp, and Slim Caps, among others. Structure and properties Phenylpropanolamine (C9H13NO, Mr = 151.21 g/mol) has a phenylethylamine structure and exists as a racemate. The salt phenylpropanolamine hydrochloride is a white … Phenylpropanolamine
Products Naphazoline is commercially available in the form of eye drops (Oculosan, Collyre bleu) in combination with other active ingredients. Decongestant nasal sprays containing naphazoline are currently no longer available in many countries. Nasal spray comp Spirig is out of trade. Structure and properties Naphazoline is often present in drugs as naphazoline nitrate (C14H15N3O3, Mr … Naphazoline
Products Epinephrine is commercially available as an injection solution and as an epinephrine auto-injector from various suppliers. The active ingredient is also known as epinephrine, especially in English (in German: Epinephrin). Structure and properties Epinephrine (C9H13NO3, Mr = 183.2 g/mol) exists as a white, crystalline powder with a bitter taste that turns brownish on contact … Adrenaline
Products Epinephrine prefilled syringes (autoinjectors) are commercially available in many countries from various suppliers. The EpiPen has been approved since 1997 and Jext since 2010. Such syringes were originally developed for the army for the administration of antidotes to chemical weapons (e.g., ComboPen in many countries). Structure and properties Epinephrine (C9H13NO3, Mr = 183.2 g/mol) … Epinephrine Prefilled Syringe (Auto-Injector)
Products Oxymetazoline cream was approved in the United States in 2017 (Rhofade, 1%). Oxymetazoline is also available as a nasal spray at a lower concentration (Nasivin); see Oxymetazoline. Structure and properties Oxymetazoline (C16H24N2O, Mr = 260.4 g/mol) is present in drugs as oxymetazoline hydrochloride, a white crystalline powder that is readily soluble in water. It … Oxymetazoline Cream
Products Buphenin was included in Arbid drops in combination with diphenylpyralin until late 2011. Structure and properties Buphenin (C19H25NO2, Mr = 299.41 g/mol), like other sympathomimetics, has structural similarity to catecholamines, for example, epinephrine. Effects Buphenine (ATC C04AA02) is β-sympathomimetic and thus vasodilatory and positively inotropic. Indications No longer commercially available in many countries for … Buphenin
