Metabolic Disorders

Addison’s Disease: Symptoms, Causes, Treatment

In Addison’s disease (synonyms: Addison’s disease; Addison’s melanosis; Addison’s syndrome; bronchial skin disease; bronchial disease; suprarenal melasma; primary adrenal insufficiency; primary adrenocortical insufficiency; primary adrenocortical atrophy; primary adrenocortical insufficiency; primary adrenocortical hypofunction; primary hypoadrenalism; primary hypoadrenocorticism; primary suprarenal insufficiency; ICD-10-GM E27. 1: Primary adrenocortical insufficiency: Addison’s disease) is primary adrenocortical insufficiency (NNR insufficiency; adrenocortical insufficiency). … Addison’s Disease: Symptoms, Causes, Treatment

Addison’s Disease: Medical History

Medical history (history of illness) represents an important component in the diagnosis of Addison’s disease. Family history Is there a frequent history of metabolic disorders in your family? Social anamnesis Current medical history/systemic history (somatic and psychological complaints). Have you noticed symptoms such as loss of appetite, abdominal pain, nausea, and vomiting? Do you feel … Addison’s Disease: Medical History

Addison’s Disease: Or something else? Differential Diagnosis

Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99). Congenital adrenal hypoplasia (underdevelopment of the adrenal glands)-genetic disorder with both autosomal dominant and autosomal recessive inheritance; severe adrenal insufficiency (adrenal weakness) manifesting shortly after birth; males exhibit pseudohermaphroditism (form of intersexuality in which the chromosomal and gonadal sexes are male) Smith-Lemli-Opitz syndrome (synonym: RSH syndrome (Opitz)) – … Addison’s Disease: Or something else? Differential Diagnosis

Addison’s Disease: Complications

The following are the most important diseases or complications that can occur as a result of underdosing* or overdosing of drug therapy in Addison’s disease: Endocrine, nutritional, and metabolic disorders (E00-E90). Diabetes mellitus (diabetes). Dwarfism* Cushing’s disease – disease caused by an increased supply of glucocorticoids. Addison’s crisis (salt wasting crisis; severe circulatory disturbances that … Addison’s Disease: Complications

Addison’s Disease: Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body temperature, body weight, body height; further: Inspection (viewing). Skin, mucous membranes and sclerae (white part of the eye) [bronze colored skin, dehydration (lack of fluids)]. Auscultation (listening) of the heart. Auscultation of the lungs … Addison’s Disease: Examination