What does the skin rash look like in case of histamine intolerance? | Histamine intolerance

What does the skin rash look like in case of histamine intolerance?

The skin rash of histamine intolerance can take on different forms and manifestations. On the one hand, simple reddening of different areas of the skin can occur. These are usually accompanied by itching.

On the other hand, symptoms of hives can also develop. The skin also reddens during this reaction and hives develop. Hives are punctiform or extensive elevations of the skin.

These elevations are caused by water retention in the skin, which is triggered by the histamine. Hives is also accompanied by itching. A third possible rash in histamine intolerance is eczema.

Eczema goes through different phases with varying degrees of severity. In the beginning, a reddish rash appears, which can form blisters in the course of time. These blisters then become encrusted and a scaly rash appears.

In the area of the face a so-called flush can occur. The flush is a medical term for blushing of the facial skin. The reaction to the histamine causes the blood vessels in the face to dilate, resulting in increased redness of the skin.

These elevations are caused by water retention in the skin, which is triggered by the histamine. Hives is also accompanied by itching. The third possible skin rash in histamine intolerance is eczema.

Eczema goes through different phases with varying degrees of severity. In the beginning, a reddish rash appears, which can form blisters in the course of time. These blisters then become encrusted and a scaly rash appears.

In the area of the face a so-called flush can occur. The flush is a medical term for blushing of the facial skin. The reaction to the histamine causes the blood vessels in the face to dilate, resulting in increased redness of the skin.

Causes

The exact cause of the development of histamine intolerance is not yet known. It can be assumed that the activity of the so-called diamine oxidase (DAO) is reduced in affected persons and thus, after eating histamine-containing food, the histamine cannot be broken down, it accumulates in the body and causes the known symptoms. The reason for the reduced activity of the enzyme is not yet known.

Since the symptoms usually occur in the course of life, it is assumed that it is not a congenital intolerance, but that it only occurs in the course of life. There are indications that tobacco smoke has an effect on the development of histamine intolerance, but there is insufficient evidence to make a clear statement on this. The symptoms that arise in the course of the disease can be explained by the natural role of histamine in the body. Thus it comes by the reduced dismantling to a so-called pseudo-allergic reaction which leads due to the histamine to typically with an allergy occurring symptoms.