Isoflavonoids have a molecular structure similar to steroidal estrogen (female sex hormone) and are therefore also called phytoestrogens. However, their hormonal activity is lower by a factor of 100 to 1,000 compared to the estrogen formed in the mammalian organism. Due to their chemical-structural similarity to the female sex hormones, isoflavones ingested with food can … Isoflavones: Functions
Interactions of isoflavones with other agents (micronutrients, foods, drugs): Drug tamoxifen Interactions of isoflavones, particularly genistein, with tamoxifen (a selective estrogen receptor modulator used as a drug for adjuvant antihormonal therapy of breast carcinoma/breast cancer when this is estrogen receptor positive) have been reported in the literature. When administered concomitantly, isoflavones may reverse the effect … Isoflavones: Interactions
Intake recommendations of the German Nutrition Society (DGE) are not yet available for these vital substances. Isoflavone content of selected foods. Daidzein content – expressed in μg – per 100 g of foodstuff Legumes Chickpeas 11,00-192,00 Soy and soy products Soy milk 1.800 Soy sausage 4.900 Tofu 7.600 Soybean seedlings 13.800 Tempeh 19.000 Miso paste … Isoflavones: Food
Animal studies are contradictory in their conclusions about the intake of soy isoflavones: Some studies showed that in an existing breast carcinoma (tumor of the mammary gland tissue), isoflavones may accelerate the growth of tumor cells. In studies on mice, the administration of isolated genistein in existing breast cancer led to increased spread of tumor … Isoflavones: Safety Assessment
