Synovitis

Inflammation of the Synovial Membrane (Synovitis): Medical History

Medical history (history of illness) represents an important component in the diagnosis of synovialitis (inflammation of the synovial membrane). Family history Social anamnesis Current anamnesis/systemic anamnesis (somatic and psychological complaints). What symptoms have you noticed? How long have these symptoms been present? Is one joint or more joints affected? Is the joint(s) swollen, overheated? Does … Inflammation of the Synovial Membrane (Synovitis): Medical History

Inflammation of the Synovial Membrane (Synovitis): Or something else? Differential Diagnosis

Blood, blood-forming organs-immune system (D50-D90). Hemophilia (hemophilia). Endocrine, nutritional, and metabolic diseases (E00-E90). Storage diseases such as Fabry disease (synonyms: Fabry disease or Fabry-Anderson disease) – X-linked lysosomal storage disease due to a defect in the gene encoding the enzyme alpha-galactosidase A, resulting in progressive accumulation of the sphingolipid globotriaosylceramide in cells; mean age of … Inflammation of the Synovial Membrane (Synovitis): Or something else? Differential Diagnosis

Inflammation of the Synovial Membrane (Synovitis): Complications

The following are the most important diseases or complications that may be contributed to by synovitis (inflammation of the synovial membrane): Infectious and parasitic diseases (A00-B99). Sepsis (blood poisoning) Musculoskeletal system and connective tissue (M00-M99). Joint capsular phlegmon – diffuse inflammation of the joint capsule caused mainly by streptococci. Hydrarthos (joint effusion) Panarthritis – complete … Inflammation of the Synovial Membrane (Synovitis): Complications

Inflammation of the Synovial Membrane (Synovitis): Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination – including blood pressure, pulse, body weight, height; furthermore: Inspection (viewing). Skin (normal: intact; abrasions/wounds, redness, hematomas (bruises), scars) and mucous membranes. Gait (fluid, limping). Body or joint posture (upright, bent, gentle posture). Malpositions (deformities, contractures, shortenings). Muscle atrophies (side … Inflammation of the Synovial Membrane (Synovitis): Examination

Inflammation of the Synovial Membrane (Synovitis): Test and Diagnosis

2nd-order laboratory parameters – depending on the results of the history, physical examination, and obligatory laboratory parameters – for differential diagnostic clarification. Small blood count Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate). Renal parameters – urea, creatinine, if necessary cystatin C or creatinine clearance. Uric acid Joint punctate Rheumatoid diagnostics – … Inflammation of the Synovial Membrane (Synovitis): Test and Diagnosis

Inflammation of the Synovial Membrane (Synovitis): Drug Therapy

Therapeutic targets Improvement of the symptomatology If necessary, elimination of the pathogens Therapy recommendations Symptomatic therapy: analgesics or anti-inflammatory drugs (non-steroidal anti-inflammatory drugs, NSAIDs), e.g. ibuprofen. Antibiotics are used in a bacterial infections initially and according to resistance spectrum. In other forms of arthritis, the underlying disease is treated See also under “Further therapy“.

Inflammation of the Synovial Membrane (Synovitis): Diagnostic Tests

Obligatory medical device diagnostics. Conventional radiographic examination of the affected joint. Optional medical device diagnostics – depending on the results of the history, physical examination and obligatory laboratory parameters – for differential diagnostic clarification. Sonography (ultrasound examination) of the affected joint [joint effusion?, erosions?] Magnetic resonance imaging(MRI; computer-assisted cross-sectional imaging method (using magnetic fields, i.e., … Inflammation of the Synovial Membrane (Synovitis): Diagnostic Tests

Inflammation of the Synovial Membrane (Synovitis): Causes

Pathogenesis (development of disease) In synovitis, an exudative inflammatory reaction (secretions) occurs in the stratum synoviale (inner layer of the joint cavity), and the synovial membrane swells. A granulocyte-rich joint effusion develops. Mobility is decreased due to worsening capsular stretching pain. Etiology (causes) Disease-related causes Allergic-related synovialitis Arthritis in: Lyme disease Psoriasis (psoriatic arthritis, PsA) … Inflammation of the Synovial Membrane (Synovitis): Causes

Inflammation of the Synovial Membrane (Synovitis): Therapy

General measures Local cooling treatment Initial immobilization and elevation of the affected joint. Nicotine restriction (refrain from tobacco use). Aim for normal weight! Determination of BMI (body mass index, body mass index) or body composition by means of electrical impedance analysis and, if necessary, participation in a medically supervised weight loss program. Conventional non-surgical therapy … Inflammation of the Synovial Membrane (Synovitis): Therapy