Uterine Fibroids

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Medical History

Medical history (history of illness) represents an important component in the diagnosis of leiomyomas/uterus myomatosus (fibroids of the uterus). Family history Are there frequent gynecologic conditions in your family? Social anamnesis Current medical history/systemic history (somatic and psychological complaints). Have you noticed any changes in menstruation? If so, what are they? Duration, strength, length of … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Medical History

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Or something else? Differential Diagnosis

Neoplasms – Tumor Diseases (C00-D48). Benign (benign)/malignant (malignant) neoplasms of the uterus (womb), unspecified (e.g., uterine sarcomas, these account for approximately 5-10% of all malignant tumors of the uterus; caveat. “fast-growing myoma” in postmenopause)Note: Among uterine sarcomas, the following subtypes are histologically distinguished: leiomyosarcoma (LMS), low-grade endometrial stromal sarcoma (LG-ESS) and high-grade endometrial stromal sarcoma … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Or something else? Differential Diagnosis

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Complications

The following are the most important diseases or complications that may be caused by leiomyomas/uterine myomatosus (fibroids of the uterus): Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99). Malformations/growth disturbances of the fetus due to forced posture. Blood, blood-forming organs – immune system (D50-D90). Iron deficiency anemia (anemia due to iron deficiency). Infectious and parasitic diseases … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Complications

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Examination

A comprehensive clinical examination is the basis for selecting further diagnostic steps: General physical examination-including blood pressure, pulse, body weight, height; further: Inspection (viewing). Skin and mucous membranes Abdominal wall and inguinal region (groin area). Gynecological examination Inspection Vulva (external, primary female sexual organs). Vagina (vagina) Cervix uteri (cervix), or portio (cervix; transition from the … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Examination

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Drug Therapy

Therapeutic Objective Improvement of symptoms by drug control of bleeding disorders (hypermenorrhea, menometrorrhagia) or preoperative reduction of fibroids. Therapy recommendations Estrogen-progestin single-phase preparations, progestin preparations, intrauterine device with progestin (levonorgestrel) for drug control of bleeding disorders. Ulipristal (ulipristal acetate; progesterone receptor modulator) for preoperative (“before surgery”) reduction of fibroids. See also under “Further therapy“. Note: … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Drug Therapy

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Diagnostic Tests

Obligatory medical device diagnostics. Vaginal ultrasonography (ultrasound using an ultrasound probe inserted into the vagina) – for bleeding disorders or palpation findings (palpation findings). Abdominal sonography (ultrasound examination of the abdominal organs) – in the case of very large fibroids (eg, the size of a child’s head) possibly in addition to vaginal sonography. Optional medical … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Diagnostic Tests

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Surgical Therapy

If the leiomyoma does not cause symptoms, it does not require therapy. If symptomatic uterus myomatosus is suspected, it should first be determined whether uterus myomatosus is actually the cause of the symptoms [S3 guideline]. An indication for therapy exists in the case of rapidly growing tumors or tumors that cause symptoms and where conservative … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Surgical Therapy

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Symptoms, Complaints, Signs

Usually, small leiomyomas/uterus myomatosus (fibroids of the uterus) do not cause symptoms and therefore tend to be diagnosed incidentally. However, the following symptoms and complaints may indicate leiomyoma/uterine myomatosus: Bleeding disorders: Hypermenorrhea (bleeding is excessive (> 80 ml); usually the affected person consumes more than five pads/tampons per day; > 40% of cases). Menorrhagia (bleeding … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Symptoms, Complaints, Signs

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Causes

Pathogenesis (development of disease) Uterine leiomyomas are benign (benign) tumors that arise from the smooth muscle of the uterus (womb). They are usually slow growing. Only during pregnancy they can also grow very quickly due to increased estrogen levels. There is no exact information about the cause of the development of leiomyomas. It is possible … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Causes

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Therapy

Conventional nonsurgical therapeutic procedures Focused ultrasound (MR-HIFU) of fibroids – MRI (magnetic resonance imaging)-guided focused ultrasound therapy (MRgFUS) (synonym: MR-HIFU = Magnetic Resonance High Intensity Focused Ultrasound) is a more recent treatment option for fibroids that is becoming increasingly important because it provides therapy with the following options: it is outpatient, has few side effects, … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Therapy

Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Test and Diagnosis

Laboratory parameters of the 1st order – obligatory laboratory tests. Small blood count (hemoglobin (Hb), hematocrit (Hct)) – to clarify myoma-related secondary anemia (anemia). Ferritin – for suspected iron deficiency anemia. Laboratory parameters 2nd order – depending on the results of the history, physical examination and obligatory laboratory parameters – for differential diagnostic clarification. Inflammatory … Uterine Fibroids (Uterus Myomatosus, Leiomyomas): Test and Diagnosis