The following are the most important diseases or complications that may be caused by leiomyomas/uterine myomatosus (fibroids of the uterus):
Congenital malformations, deformities, and chromosomal abnormalities (Q00-Q99).
- Malformations/growth disturbances of the fetus due to forced posture.
Blood, blood-forming organs – immune system (D50-D90).
Infectious and parasitic diseases (A00-B99).
- Infection, especially of submucosal leiomyomas, unspecified.
Pregnancy, childbirth, and puerperium (O00-O99).
- Abortion (miscarriage)
- Atonic hemorrhage – massive bleeding after childbirth due to uterine atony (weakness of contraction of the uterus).
- Premature birth
- Placental abruption
Genitourinary system (kidneys, urinary tract – reproductive organs) (N00-N99)
- Capsular rupture
- Female sterility/infertility
- Pedunculated subserosal leiomyoma possibly with signs of acute abdomen.
Since the blood supply of leiomyomas is very limited, secondary changes such as:
- Hyaline degeneration – leads to a softer consistency.
- Calcification (calcification)
- Necrosis (= myoma necrosis) – local tissue death in a myoma.
- Parasitic fibroids – in this case, the leiomyomas grow together with the peritoneum (peritoneum) or other organs, which take over the blood supply instead of the uterus, due to an inflammatory reaction
- Cystic degeneration – with formation of cavities within the leiomyoma.
