2nd order laboratory parameters – depending on the results of the history, physical examination, and obligatory laboratory parameters – for differential diagnostic clarification.
- Herpes simplex virus type 1 antibodies (IgG; IgM).
- Herpes simplex virus type 1 virus culture from vesicle contents.
- HSV-1 PCR – direct detection of viral DNA by PCR (polymerase chain reaction) from efflorescences.
- Immunofluorescence (antibody staining).
- Electron microscopic direct detection
