How does grading influence the survival rate?
Grading involves looking at the tumor cells under the microscope. The pathologist evaluates how far the tumor cells have differentiated from the original tissue. Classically, the tumor tissue is divided into three grades.
In the case of breast cancer, the grading is carried out according to the Elston and Ellis system. G1 is still closest to the tissue of origin, but is already considered malignant, while G3 is a poorly differentiated tissue that does not bear much resemblance to the origin. A G2 tumor still shows moderately differentiated malignant tissue.
Grading G1 has the best prognosis, also in terms of survival rate, as these tumors show a more favorable course. G3 tumors show more often an aggressive and fast growth and are therefore associated with a worse survival rate. This topic might also be of interest to you: Tumor markers in breast cancer
