Nocturnal Urination (Nocturia): Test and Diagnosis

Laboratory parameters of the 1st order – obligatory laboratory tests.

  • Urine status (rapid test for: pH, leukocytes, nitrite, protein, glucose, blood), sediment.
  • Urine culture (pathogen detection and resistogram, that is, testing suitable antibiotics for sensitivity/resistance).

Laboratory parameters 2nd order – depending on the results of the history, physical examination and the obligatory laboratory parameters – for differential diagnostic clarification.

  • Small blood count
  • Differential blood count
  • Inflammatory parameters – CRP (C-reactive protein) or ESR (erythrocyte sedimentation rate).
  • Fasting glucose (fasting blood glucose).
  • Potassium
  • Thyroid parameters – TSH (thyroid-stimulating hormone) – if hyperthyroidism is suspected.
  • Liver parameters – alanine aminotransferase (ALT, GPT), aspartate aminotransferase (AST, GOT), glutamate dehydrogenase (GLDH) and gamma-glutamyl transferase (gamma-GT, GGT), alkaline phosphatase, bilirubin.
  • Renal parameters – urea, creatinine, cystatin C or creatinine clearance, if necessary.
  • NT-proBNP (N-terminal pro brain natriuretic peptide) – if heart failure (cardiac insufficiency) is suspected.
  • Thirst test (two-step test) – diagnostic test to rule out diabetes insipidus.
  • PSA (prostate specific antigen).