Pathogenesis (disease development)
The exact cause of polymorphous light dermatosis is not known. In recent studies, it is thought that immune regulation is disrupted after UV exposure. About 75% of affected individuals have exclusive UV-A sensitivity. 15% show UV-A/B sensitivity.
It has been observed that polymorphous light dermatosis also occurs from sun exposure behind window glass.
Etiology (Causes)
Biographic causes
- Occupations – occupations with high UV exposure.
Environmental exposure – intoxications (poisonings).
- Exposure to light is the triggering factor!
