Avoidance of complications (as far as possible) – patients with immunodeficiency (antibody deficiency syndromes, HIV infection), hematopoietic disorders and pregnant women are at risk.
Therapy recommendations
Symptomatic therapy (analgesics (painkillers), antipyretics (antipyretic drugs), if necessary); in most cases, no drug therapy is necessary
Pregnancy: in acute B19 infection of a pregnant woman, prophylactic administration of immunoglobulins to prevent transplacental (“across the placenta“) transmission is not indicated; however, close monitoring by Doppler sonography must be performed to diagnose fetal anemia (fetal anemia) in a timely manner. In such cases, intrauterine (“inside the womb”) exchange transfusions are required.
In immunocompromised patients, persistent (continuing) infections can be treated by high-dose immunoglobulin administration.
If fetal anemia (infantile anemia) is suspected, consider intrauterine transfusion of erythrocytes (red blood cells) (IUT) (see “Further Therapy” below).
