Shortness of Breath (Dyspnea): Medical History

Medical history (history of illness) represents an important component in the diagnosis of dyspnea (shortness of breath). Family history

  • What is the general health of your family members?
  • Are there any cardiovascular or respiratory diseases in your family that are common?

Social history

  • What is your profession?
  • Are you exposed to harmful working substances in your profession?

Current medical history/systemic medical history (somatic and psychological complaints).

  • How long has the shortness of breath been present?
  • Graduation of pulmonary dyspnea (lung-related shortness of breath) according to the modified Medical Research Council (MRC) suggestions:
    • Grade 0: “I never have dyspnea except on vigorous exertion.”
    • Grade 1: “I have shortness of breath when walking fast or walking uphill with a slight incline”
    • Grade 2: “I walk slower than peers when walking on level ground or require breaks at self-selected speeds”
    • Grade 3: “I require a break due to shortness of breath when walking on level ground after 100 m or a few minutes”
    • Grade 4: “I am too short of breath to leave the house or to get dressed or undressed”
  • Is the shortness of breath
    • Come on suddenly?
    • Episodic (temporary)?
    • Slowly progressive (advancing)?
    • Rapidly progressive (advancing)?
  • What is the dyspnea?
    • When breathing in?
    • Exhale?
    • At rest?
    • Under load?
    • Cough-dependent?
  • Was there a direct trigger?
  • Is the dyspnea seizure or positional?
  • How many pillows do you use to sleep?
  • Can you lie flat without getting too little air?
  • Did the shortness of breath occur from one breath to the next? *
  • How severe is the shortness of breath?
  • Do you have other symptoms such as fever, cough, etc.? *
  • Do you experience any viscous sputum? Coughing fits? *
  • Does a feeling of tightness in the chest then also occur? *
  • When do these symptoms occur? Depending on the time of year? Depending on other factors?
  • Have you had a respiratory infection recently?
  • Do you have calf pain?
  • Do you have a lot of stress?

Vegetative anamnesis including nutritional anamnesis.

  • Do you smoke? If yes, how many cigarettes, cigars or pipes per day?
  • Is there smoking in your neighborhood?
  • Do you live in the city or in the countryside (in terms of air pollution)?
  • Do you drink alcohol? If so, what drink(s) and how many glasses per day?
  • Do you use drugs? If yes, what drugs and how often per day or per week?
  • Has there been any change in your appetite?
  • Have you noticed any unwanted change in weight?
  • Have you noticed any changes in digestion and/or water excretion?
  • Do you suffer from sleep disturbances?

Self-history

Medication history

  • Antineoplastic agents (other antineoplastic agents [eg, protein kinase inhibitors], antimetabolites).
  • Amiodarone (antiarrhythmic agent) → interstitial pneumonitis (collective term for any form of lung inflammation (pneumonia) that affects the interstitium or intercellular space rather than the alveoli (pulmonary alveoli))
  • Beta-blockers, non-selective (propranolol, pindolol, carvedilol).
  • Cox inhibitors (e.g., acetylsalicylic acid, indomethacin) – inhibition of cyclooxygenases (COX) increases the conversion of arachidonic acid from lipoxygenase to leukotrienes, which can trigger an asthma attack
  • Monoclonal antibodies – pertuzumab
  • MTOR inhibitors (everolimus, temsirolimus).
  • Nitrofurantoin (antibiotic).
  • Opioids (painkillers that have an analgesic effect at the so-called opioid receptors; e.g., morphine).
  • X-ray contrast media (as an immediate reaction).
  • Platelet aggregration inhibitors (e.g.B. acetylsalicylic acid, ticagrelor).

* If this question has been answered with “Yes”, an immediate visit to the doctor is required! (Data without guarantee)