Antithrombotics

Effects Antithrombotic Anticoagulant Fibrinolytic Active ingredients Salicylates: Acetylsalicylic acid 100 mg (Aspirin Cardio). P2Y12 antagonists: Clopidogrel (Plavix, generics). Prasugrel (Efient) Ticagrelor (Brilique) GP IIb/IIIa antagonists: Abciximab (ReoPro) Eptifibatide (Integrilin) Tirofiban (Aggrastat) PAR-1 antagonists: Vorapaxar (Zontivity) Vitamin K antagonists (coumarins): Phenprocoumon (Marcoumar). Acenocoumarol (Sintrom) Not on sale in many countries: dicoumarol, warfarin. Heparins: Heparin sodium Heparin-Calcium … Antithrombotics

Monoclonal Antibodies

Products The first therapeutic monoclonal antibody was approved in 1986. Muromonab-CD3 (Orthoclone OKT3) binds to the CD3 receptor on T cells and has been used in transplantation medicine. Numerous drugs containing antibodies are now available. A selection of active substances can be found at the end of this article. These are expensive drugs. For example, … Monoclonal Antibodies

Platelets

Introduction Blood platelets, or thrombocytes, are cells in the blood that play an important role in blood clotting, i.e. stopping bleeding. Along with red blood cells and immune cells (leukocytes), they are one of the main components of the blood. The technical term thrombocyte for blood platelets is derived from the Greek von thrombos for … Platelets

Blood platelet count too high | Platelets

Blood platelet count too high If the platelets in the blood are elevated (>500. 000/μl), this is called thrombocytosis. These can be either primary (congenital, genetic) or secondary (acquired, caused by another disease). Secondary thrombocytosis is usually caused by infections, chronic inflammatory diseases, tissue injuries or certain forms of anaemia. Infections in which elevated platelet … Blood platelet count too high | Platelets