Capsules

Definition Capsules are solid and single-dose dosage forms of medicine of various shapes and sizes, usually intended for ingestion. This article refers to hard capsules. Soft capsules are covered in a separate article. Hard capsules, unlike them, do not contain plasticizers. Capsules consist of a capsule shell and the filling material, which contains the active … Capsules

Release (Liberation)

Definition After a drug is ingested, it passes through the esophagus into the stomach and into the small intestine. There, the active ingredient must first be released from the dosage form. This is the prerequisite for it to be absorbed into the bloodstream via the cells of the mucosa. The dosage form thus exerts a … Release (Liberation)

Tenapanor

Products Tenapanor was approved in the United States in tablet form in 2019 (Ibsrela). Structure and properties Tenapanor (C50H66Cl4N8O10S2, Mr = 1145 g/mol) is present in the drug as tenapanor hydrochloride, a white to light brown, amorphous, and hygroscopic substance that is practically insoluble in water. Because of its high molecular mass and polar surface … Tenapanor

Naproxen: Drug Effects, Side Effects, Dosage and Uses

Products Naproxen has been approved in many countries since 1975 and is commercially available in the form of film-coated tablets (e.g., Apranax, Proxen, generics). Other dosage forms such as the suppositories and the juice are no longer available. Drugs with a deep dose have been available over the counter since 1999 (Aleve with 200 mg … Naproxen: Drug Effects, Side Effects, Dosage and Uses