Products Sputnik V is a Covid-19 vaccine developed in Russia and the first vaccine from this group to be registered on August 11, 2020 (Gamaleya National Center of Epidemiology and Microbiology). The name is derived from the Sputnik satellite, which was the first satellite placed in Earth orbit by the Soviet Union in 1957. Sputnik … Sputnik V
Products NZT is a (fictional) agent from the film (2011) based on the novel by Alan Glynn. The film was additionally followed in 2015 by a TV series with the same title, which was canceled after just one season. NZT belongs to the drug group of smart drugs. Structure and properties NZT is thallanylzirconio-methyl-tetrahydro-triazatriphenylene. The … NZT
Products Nadroparin is commercially available as a solution for injection (Fraxiparine, Fraxiforte). It has been approved in many countries since 1988. Structure and properties Nadroparin is present in the drug as nadroparin calcium. It is the calcium salt of a low-molecular-weight heparin obtained by depolymerization of heparin from the intestinal mucosa of pigs using nitrous … Nadroparin
Products Benzhydrocodone was approved in the United States in 2018 as a fixed combination with acetaminophen in tablet form with a modified release of active ingredient (Apadaz). Structure and properties Benzhydrocodone (C25H25NO4, Mr = 403.5 g/mol) is an inactive prodrug of hydrocodone. It is an ester of benzoic acid with the opioid that is enzymatically … Benzhydrocodone
Products Benzododecinium bromide is commercially available in many countries as a solution for nasal use in combination with sodium chloride and polysorbate 80 (Prorhinel). Structure and properties Benzododecinium bromide (C21H38BrN, Mr = 384.4 g/mol) is a quaternary ammonium base. Effects Benzododecinium bromide (ATC D09AA05) has disinfectant properties. Indications The solution is used to treat nasal … Benzododecinium Bromide
Products Benzoxonium chloride is commercially available in the form of sprays, as a solution, and lozenges (e.g., Merfen with chlorhexidine). Usually, these are combination preparations. Structure and properties Benzoxonium chloride (C23H42ClNO2, Mr = 400.0 g/mol) is a quaternary ammonium compound. Effects Benzoxonium chloride (ATC A01AB14, ATC D08AJ05) has antiseptic properties against bacteria, viruses, and fungi. … Benzoxonium Chloride
Products In many countries, human drugs containing ampicillin are no longer commercially available. In other countries, film-coated tablets and injectables are available, often in fixed combination with sulbactam. Structure and properties Ampicillin (C16H19N3O4S, Mr = 349.4 g/mol) exists as a white crystalline powder that is sparingly soluble in water. In contrast, the sodium salt ampicillin … Ampicillin (Polycillin, Principen, Omnipen)
Products Sulfaguanidine is commercially available in combination preparations as a powder for animals. Structure and properties Sulfaguanidine (C7H10N4O2S, Mr = 214.2 g/mol) is a sulfonamide and guanidine derivative. Effects Sulfaguanidine (ATCvet QA07AB03) has antibacterial properties. It acts mainly locally in the digestive tract, as it is hardly absorbed into the organism. Indications Diarrheal diseases in … Sulfaguanidine
Products Anturan dragées are no longer on sale in many countries. Structure and properties Sulfinpyrazone (C23H20N2O3S, Mr = 404.5 g/mol) is a white powder that is sparingly soluble in water. Effects Sulfinpyrazone (ATC M04AB02) is uricosuric and antiplatelet. Indications Gout Reinfarct prophylaxis Thrombosis prophylaxis
Products Cefalexin is commercially available as a veterinary drug in the form of tablets, chewable tablets, and suspensions. It is available both as a monopreparation (e.g., Cefacat, Cefadog) and in combination with kanamycin (Ubrolexin). It has been approved in many countries since 1986. Structure and properties Cefalexin (C16H17N3O4S , Mr = 347.4 g/mol) exists as … Cefalexin
Products Benralizumab was approved as a solution for injection in the United States in 2017 and in the EU and many countries in 2018 (Fasenra). Structure and properties Benralizumab is a humanized and afucosylated IgG1κ antibody with a molecular mass of 150 kDa. It is produced by biotechnological methods. Omission of the fucose in the … Benralizumab
Products Reteplase was marketed as an injectable (Rapilysin). The drug was approved in many countries in 1996 and withdrawn from the market in 2013. Structure and properties Reteplase is derivative of tissue-specific plasminogen activator (t-PA). It is a serine protease containing 355 of the 527 amino acids of native t-PA. The protein is produced by … Reteplase