Products Rizatriptan is commercially available in tablet and lingual (melting) tablet form (Maxalt, generics). It has been approved in many countries since 2000. Generic versions went on sale in 2015. Structure and properties Ritatriptan (C15H19N5, Mr = 269.3 g/mol) is present in drugs as rizatriptan benzoate, a white crystalline powder that is soluble in water. … Rizatriptan
Products Quinagolide is commercially available in tablet form (Norprolac). It has been approved in many countries since 1994. Structure and properties Quinagolide (C20H33N3O3S, Mr = 395.56 g/mol) is a non-ergoline dopamine agonist with a similar structure to apomorphine. It is present in drugs as quinagolide hydrochloride. Effects Quinagolide (ATC G02CB04) has dopaminergic properties and inhibits … Quinagolide
Products Obeticholic acid is commercially available in the form of film-coated tablets (Ocaliva). It has been approved in the EU and US since 2016 and in many countries since 2018. Structure and properties Obeticholic acid (C26H44O4, Mr = 420.6 g/mol) exists as a white powder that is highly soluble in water at a high pH. … Obeticholic Acid
Products Sumatriptan is commercially available as film-coated tablets, nasal spray, injectable solution, and suppositories (Imigran, generics). It has been approved in many countries since 1993. Structure and properties Sumatriptan (C14H21N3O2S, Mr = 295.4 g/mol) is present in drugs as sumatriptan or in the form of the salt sumatriptan succinate. Sumatriptan succinate is a white powder … Sumatriptan
Products Dextromethorphan is available in the form of tablets, lozenges, sustained-release capsules, syrup, and drops, among others (in many countries, for example, Bexin, Calmerphan, Calmesin, Pulmofor, combination preparations). The first drugs came on the market in the 1950s. Structure and properties Dextromethorphan (C18H25NO, Mr = 271.4 g/mol) was developed as an analog of codeine and … Dextromethorphan
Products Cariprazine was approved in the United States in 2015 and in many countries and the EU in 2018 in capsule form (Reagila, some countries: Vraylar). Structure and properties Cariprazine (C21H32Cl2N4O, Mr = 427.4 g/mol) is a piperazine and dimethylurea derivative. It is present in the drug as cariprazine hydrochloride, a white powder. Active metabolites … Cariprazine
Products Anti-allergy medications are available in numerous dosage forms. These include tablets, capsules, solutions, suspensions, nasal sprays, eye drops, inhalation preparations, and injectables. Structure and properties Antiallergic drugs do not have a uniform chemical structure. However, several groups within the class can be identified (see below). Effects Antiallergic drugs have antiallergic, antiinflammatory, immunosuppressive, antihistamine, and … Antiallergics
Products Moxonidine is commercially available in tablet form (Physiotens). It has been approved in many countries since 1993. Structure and properties Moxonidine (C9H12ClN5O, Mr = 241.7 g/mol) exists as a white powder that is very sparingly soluble in water. It is an imidazoline derivative structurally related to clonidine. Effects Moxonidine (ATC C02AC05) has central antihypertensive … Moxonidine
Products Sympathomimetics are commercially available, for example, in the form of tablets, capsules, granules, injectable solutions, eye drops, and nasal sprays. Structure and properties Sympathomimetics are structurally derived from the natural neurotransmitters epinephrine and norepinephrine. Effects Sympathomimetics have sympathomimetic properties, meaning that they promote the effects of the sympathetic nervous system, a portion of the … Sympathomimetics
Products Olodaterol was approved in many countries in 2014 as a solution for inhalation (Striverdi). In 2016, a fixed-dose combination with tiotropium bromide was also marketed (Spiolto). Both drugs are administered with the Respimat. Respimat The Respimat is a new inhalation device that releases a visible spray, or aerosol. The droplets are fine and move … Olodaterol
Products Eletriptan is commercially available in the form of film-coated tablets (Relpax, generics). It has been approved in many countries since 2000. Structure and properties Eletriptan (C22H26N2O2S, Mr = 382.5 g/mol) is a lipophilic methylpyrrolidinyltryptamine substituted with a sulfonylbenzene. It is present in drugs as eletriptan hydrobromide, a white powder that is readily soluble in … Eletriptan
Products Buprenorphine is commercially available as sublingual tablets, transdermal patch and injection solution, and depot injection solution (e.g., Temgesic, Transtec, Subutex, generics). It has been approved in many countries since 1979. Structure and properties Buprenorphine (C29H41NO4, Mr = 467.6 g/mol) is present in drugs as buprenorphine hydrochloride, a white crystalline powder that is sparingly soluble … Buprenorphine
