Products Bremelanotide was approved in the United States in 2019 as an injection solution in an auto-injector pen (Vyleesi). Structure and properties Bremelanotide (C50H68N14O10, Mr = 1025.2 g/mol) is a synthetic cyclic peptide analog of α-melanocyte stimulating hormone (α-MSH) produced in the adenohypophysis. Bremelanotide consists of seven amino acids (heptapeptide) and is an active metabolite … Bremelanotide
Products Brexpiprazole was approved in the United States in 2015 and in the EU and many countries in 2018 in film-coated tablet form (Rexulti). Structure and properties Brexpiprazole (C25H27N3O2S, Mr = 433.6 g/mol) is structurally closely related to aripiprazole (Abilify, generics). Effects Brexpiprazole (ATC N05AX16) has antipsychotic properties. The effects are due to partial agonism … Brexpiprazole
Products Aripiprazole is commercially available in tablet, meltable tablet, syrup, solution for injection, and sustained-release injection suspension forms (Abilify, Abilify Maintena, generics). It has been approved in many countries since 2004 and in the United States since 2002. Generics entered the market in 2015. Also used is the prodrug aripiprazollauroxil (Aristada). Structure and properties Aripiprazole … Aripiprazole
Products Aripiprazollauroxil was newly approved in the United States in 2015 as a suspension for injection (Aristada). It has not yet been registered in many countries. Structure and properties Aripiprazollauroxil (C36H51Cl2N3O4, Mr = 660.7 g/mol) is the ester of -hydroxymethyl aripiprazole and lauric acid. Aripiprazollauroxil is a prodrug of aripiprazole (Abilify, generic). Unlike oral aripiprazole, … Aripiprazollauroxil
Products Tetryzoline is commercially available in the form of eye drops (Visine Classic, combination products). It has been approved in many countries since 1959. The active ingredient is also known as tetrahydrozoline. Nasal sprays or [nasal drops containing tetryzoline are currently no longer available in many countries. Structure and properties Tetryzoline (C13H16N2, Mr = 200.3 … Tetryzoline: Drug Effects, Side Effects, Dosage and Uses
Products Phenylephrine is commercially available in the form of eye drops (Neosynephrine-POS 5%). Structure and properties Phenylephrine(C9H13NO2, Mr = 167.2 g/mol) is a derivative of epinephrine. It exists as phenylephrine hydrochloride, a white crystalline powder that is readily soluble in water. The drug contains the pure -enantiomer. Effects Phenylephrine (ATC S01FB01) has mydriatic and vasoconstrictor … Phenylephrine Eye Drops
Products Naratriptan is commercially available in the form of film-coated tablets (Naramig). It has been approved in many countries since 1997. Structure and properties Naratriptan (C17H25N3O2S, Mr = 335.5 g/mol) is structurally related to serotonin and is an indole and piperidine derivative. It is present in drugs as naratriptan hydrochloride, a white to slightly yellowish … Naratriptan: Drug Effects, Side Effects, Dosage and Uses
Products Epinephrine is commercially available as an injection solution and as an epinephrine auto-injector from various suppliers. The active ingredient is also known as epinephrine, especially in English (in German: Epinephrin). Structure and properties Epinephrine (C9H13NO3, Mr = 183.2 g/mol) exists as a white, crystalline powder with a bitter taste that turns brownish on contact … Adrenaline
Products Oxymetazoline cream was approved in the United States in 2017 (Rhofade, 1%). Oxymetazoline is also available as a nasal spray at a lower concentration (Nasivin); see Oxymetazoline. Structure and properties Oxymetazoline (C16H24N2O, Mr = 260.4 g/mol) is present in drugs as oxymetazoline hydrochloride, a white crystalline powder that is readily soluble in water. It … Oxymetazoline Cream
Products Oxymorphone is commercially available in the United States as tablets and sustained-release tablets and has also been administered parenterally and rectally. It is not registered in many countries. Oxymorphone has been approved in the U.S. since 1959 (brand names: Numorphan, Opana, Opana ER, generics). It is a narcotic drug. Due to the potential for … Oxymorphone
Products Ozanimod was approved in the United States and many countries in 2020 in hard capsule form (Zeposia). Structure and properties Ozanimod (C23H24N4O3, Mr = 404.5 g/mol) is present in the drug as ozanimod hydrochloride, a white solid that is highly soluble in water. Active metabolites are involved in the effects. Effects Ozanimod (ATC L04AA38) … Ozanimod
