Products Formoterol is commercially available in the form of capsules for inhalation (Foradil) and as a powder inhaler (Oxis). Furthermore, combination products with budesonide (Symbicort Turbuhaler, Vannair Dosieraerosol) and fluticasone propionate are available (Formoterol Dosieraerosol). Formoterol is also combined with beclometasone fixed, see under beclometasone and formoterol (Foster). Furthermore, in 2020, a fixed combination with … Formoterol
Products Triptans are mainly taken in the form of film-coated tablets and melting tablets. Some are also available as subcutaneous injectable solutions and nasal sprays. Suppositories are no longer commercially available in many countries. Sumatriptan (Imigran) was the first agent in this group to be approved in the United States in 1992 and in many … Triptans: Drug Effects, Side Effects, Dosage and Uses
Products Nalbuphine is commercially available as a solution for injection (Nalbuphine OrPha). It has been approved in many countries since 2004. Structure and properties Nalbuphine (C21H27NO4, Mr = 357.4 g/mol) is a morphine derivative structurally related to naloxone and oxymorphone. It is present in drugs as nalbuphine hydrochloride. Effects Nalbuphine (ATC N02AF02) has analgesic properties. … Nalbuphin
Products Diphenhydramine is commercially available in tablet, drop, and gel forms (e.g., Benocten, Nardyl Sleep, Fenipic plus), among others. It is also known as Benadryl in some countries. Diphenhydramine was developed in the 1940s. It is also a component of the active ingredient dimenhydrinate. Structure and properties Diphenhydramine (C17H21NO, Mr = 255.4 g/mol) is present … Diphenhydramine
Products Mescaline, peyote, and San Pedro are among the banned narcotics in many countries and are therefore generally not legally available. Structure and properties Mescaline (C11H17NO3, Mr = 211.3 g/mol) is a trimethoxy-phenylethylamine derivative with a bitter taste (3,4,5-trimethoxyphenylethylamine). Mescaline is structurally related to catecholamines such as epinephrine and to ecstasy, among others. Origin Mescaline … Mescaline
Products Agomelatine is commercially available in the form of film-coated tablets (Valdoxan, generic). It was approved in the EU in 2009 and in many countries in 2010. Structure and properties Agomelatine (C15H17NO2, Mr = 243.30 g/mol) exists as a white powder that is practically insoluble in water. It is a naphthalene analog of the epiphyseal … Agomelatine
Products Prostaglandin analogues are commercially available in the form of eye drops in vials or as monodoses without preservatives. Latanoprost (Xalatan) was the first agent from this group to be approved in 1996. Prostaglandin analogues are also combined with the beta-blocker timolol fix. Structure and properties Prostaglandin analogs are derivatives of prostaglandin F2α. Except for … Prostaglandin Analogs
Products Regadenoson is commercially available as a solution for injection (Rapiscan). It was approved in the United States in 2008, in the EU in 2010, and in many countries in 2017. Structure and properties Regadenoson (C15H18N8O5, Mr = 390.4 g/mol) is present in the drug as a monohydrate. It is a derivative of adenosine. Effects … Regadenoson
Products Xylometazoline is commercially available in the form of nasal sprays and as nasal drops (Otrivin, generics, combination products, for example with dexpanthenol). It was developed at Ciba and has been approved in many countries since 1958. Structure and properties Xylometazoline is present in drugs as xylometazoline hydrochloride (C16H24N2 – HCl, Mr = 280.8 g/mol), … Xylometazoline
Products Travoprost is commercially available in the form of eye drops as a monopreparation (Travatan) and as a fixed combination with the beta-blocker timolol (Duotrav). It was approved in many countries in 2002. Generic versions were first released in 2016 and went on sale in 2017. Structure and properties Travoprost (C26H35F3O6, Mr = 500.55 g/mol) … Travoprost
Products Bromocriptine is commercially available in tablet form (Parlodel). It was developed at Sandoz in the 1960s and has been approved in many countries since 1975. Generic versions are now available in many countries. Structure and properties Bromocriptine (C32H40BrN5O5, Mr = 654.6 g/mol) is a brominated derivative of the natural ergot alkaloid ergocryptine. It is … Bromocriptine
Products Trifarotene was approved as a cream in the United States in 2019 and in Germany and many countries in 2020 (Aklief, Selgamis). Structure and properties Trifarotene (C29H33NO4, Mr = 459.6 g/mol) is a derivative of a terphenylic acid. It exists as a white to slightly yellow powder that is practically insoluble in water. Effects … Trifarotene
