Hydroxylation: Function, Role & Diseases

Hydroxylations are chemical reactions that involve the introduction of hydroxyl groups into a molecule. In the context of metabolism, enzymes provide the catalysis of hydroxylations. The corresponding enzymes are called hydroxylases. What is hydroxylation? In the context of metabolism, enzymes provide catalysis of hydroxylations. The corresponding enzymes are called hydroxylases. Hydroxylations are very common in … Hydroxylation: Function, Role & Diseases

Mineralocorticoids: Function & Diseases

Mineralocorticoids are hormones that belong to the corticosteroids. The hormones play an important role in regulating blood pressure and sodium/potassium balance. What are mineralocorticoids? Mineralocorticoids are steroid hormones made by the adrenal gland. Steroid hormones are steroids with hormonal effects. Steroids belong to the lipid class of substances. Lipids are molecules that have lipophilic groups … Mineralocorticoids: Function & Diseases

Endocrine Secretion: Function, Role & Diseases

Endocrine secretion refers to the release of hormones or mediators (messengers) into the blood. The endocrine glands are responsible for secretion. The released agents are effective even at the lowest concentrations. What is endocrine secretion? Endocrine secretion refers to the release of hormones or mediators (messengers) into the blood. The endocrine glands, such as the … Endocrine Secretion: Function, Role & Diseases

Adrenocortical Insufficiency: Causes, Symptoms & Treatment

In adrenocortical insufficiency, the adrenal cortex can no longer produce enough hormones. A distinction must be made between primary and secondary adrenocortical insufficiency based on location. What is adrenocortical insufficiency? Schematic diagram showing the anatomy and structure of the adrenal gland. Click to enlarge. Approximately 5 in 100,000 people suffer from this rare disease. Primary … Adrenocortical Insufficiency: Causes, Symptoms & Treatment

Renin-Angiotensin-Aldosterone System (RAAS)

Effects The RAAS is activated in the presence of low blood pressure, decreased blood volume, hyponatremia, and sympathetic activation. Main actions: mediated via angiotensin II: Vasoconstriction Blood pressure increase Release of catecholamines Hypertrophy at the heart Mediated via aldosterone: Water and sodium ions are retained Potassium ions and protons are eliminated Overview of the RAAS … Renin-Angiotensin-Aldosterone System (RAAS)

Corticosterone: Function & Diseases

Corticosterone is a steroid hormone produced in the adrenal cortex. Among other things, it serves to synthesize aldosterone. What is corticosterone? Just like cortisone, corticosterone belongs to the steroid hormones. Steroid hormones are hormones that are built from a steroidal backbone. This skeleton is derived from cholesterol. Cholesterol is an alcohol that belongs to the … Corticosterone: Function & Diseases

Adynamia: Causes, Symptoms & Treatment

Adynamia refers to a state of general exhaustion and marked listlessness. It occurs as a result of various physical and mental disorders. What is adynamia? Adynamia refers to a state of general exhaustion and marked listlessness. Adynamia is not a disease in its own right, but rather a symptom. Regardless of its origin, this symptom … Adynamia: Causes, Symptoms & Treatment

Primary Hyperaldosteronism: Causes, Symptoms & Treatment

The clinical picture of primary hyperaldosteronism is also known as Conn syndrome. It is characterized by elevated levels of the hormone aldosterone, which increases blood pressure. What is primary hyperaldosteronism? Underlying primary hyperaldosteronism in most cases is either hyperplasia of the adrenal cortex or adrenocortical adenoma. The result is increased production of the hormone aldosterone. … Primary Hyperaldosteronism: Causes, Symptoms & Treatment

Licorice: Intolerance & Allergy

The term licorice is used for the extract from the root of the licorice (raw licorice) as well as for finished confectionery products that contain raw licorice as a basic substance. In addition, the extract was already used in ancient times as an expectorant and mucolytic as well as an anti-inflammatory and antispasmodic agent. Especially … Licorice: Intolerance & Allergy