5Α-Reductase Inhibitors

Products 5α-Reductase inhibitors are commercially available in many countries in the form of film-coated tablets and capsules. Finasteride was the first agent from this group to be approved in 1993 (USA: 1992). There are two finasteride drugs on the market. One with 5 mg for the treatment of prostate enlargement (Proscar, generic) and one with … 5Α-Reductase Inhibitors

Alfatradiol

Products In many countries, no finished medicinal products containing alfatradiol are commercially available. In Germany, preparations for external use are available (e.g., Ell-Cranell). Structure and properties Alfatradiol (C18H24O2, Mr = 272.4 g/mol) or 17α-estradiol is a stereoisomer of the female sex hormone 17β-estradiol. Effects Alfatradiol inhibits the enzyme 5α-reductase, thereby inhibiting the synthesis of the … Alfatradiol

Androgenetic Alopecia in Women

Symptoms Increasing diffuse thinning of the hair occurs in the area of the middle parting. In this case, unlike androgenetic alopecia in men, not all hair is lost, but the scalp becomes visible over time. Often, a densely hairy strip remains frontally above the forehead. Dense hair is also still found on the sides and … Androgenetic Alopecia in Women

Androgenetic Alopecia in Men

Symptoms Hereditary hair loss in men begins at the temples (“receding hairline”) and continues to the crown and back of the head, with progressive thinning and the typical M-shaped pattern. Over time, all that may remain of the once lush head of hair is a bald spot and a crown of hair. Unlike telogen effluvium, … Androgenetic Alopecia in Men