Hyperhomocysteinemia: Therapy

General measures

  • Nicotine restriction (refraining from tobacco use).
  • Limited alcohol consumption (men: max. 25 g alcohol per day; women: max. 12 g alcohol per day).
  • Aim for normal weight! Determination of BMI (body mass index, body mass index) or body composition by means of electrical impedance analysis and, if necessary, participation in a medically supervised weight loss program.
    • BMI ≥ 25 → participation in a medically supervised weight loss program.
  • Review of permanent medication due topossible impact on the existing disease.
  • Avoidance of psychosocial stress:
    • Stress

Regular checkups

  • Regular medical checkups

Nutritional medicine

  • Nutritional counseling based on nutritional analysis
  • Nutritional recommendations according to a mixed diet taking into account the disease at hand. This means, among other things:
    • A total of 5 servings of fresh vegetables and fruit daily (≥ 400 g; 3 servings of vegetables and 2 servings of fruit).
    • Once or twice a week fresh sea fish, i.e. fatty marine fish (omega-3 fatty acids) such as salmon, herring, mackerel.
    • High-fiber diet (whole grains, vegetables).
  • Observance of the following special dietary recommendations:
    • Hyperhomocysteinemia can be effectively treated by an increased intake of vitamin B6, vitamin B12 and especially folic acid.
    • Diet rich in:
      • Vitamins (vitamins B6, B12, folic acid) – A folic acid intake of 400 µg/day can be achieved by a high consumption of vegetables, fruits and whole grain cereals. Vitamin B12 requirements can be met in particular by increasing intake of milk and dairy products, lean meat and fish. Vitamin B6 is absorbed mainly through the consumption of legumes, edible bran, fish and nuts.
      • Omega-3 fatty acids (sea fish)
  • Selection of appropriate food based on the nutritional analysis
  • See also under “Therapy with micronutrients (vital substances)” – if necessary, taking a suitable food supplement (supplementation).
    • In case of hyperhomocysteinemia > 10 μmol/l:
    • In the case of polymorphism of methylenetetrahydrofolate reductase (MTHFR): taking the active folic acid form 5-MTHF in homozygous trait carriers.
  • For detailed information on nutritional medicine, please contact us.

Sports Medicine

Psychotherapy