Absinthe

Products Absinthe is available, for example, in liquor stores. The production and distribution were prohibited in many countries between 1910 and 2005. However, during this time, it is known that it was distilled illegally. Today absinthe can be sold legally again. The drink originated in the late 18th century in Val-de-Travers in the canton of … Absinthe

Antiallergics

Products Anti-allergy medications are available in numerous dosage forms. These include tablets, capsules, solutions, suspensions, nasal sprays, eye drops, inhalation preparations, and injectables. Structure and properties Antiallergic drugs do not have a uniform chemical structure. However, several groups within the class can be identified (see below). Effects Antiallergic drugs have antiallergic, antiinflammatory, immunosuppressive, antihistamine, and … Antiallergics

Antiandrogens

Products Antiandrogens are mainly commercially available in the form of tablets, capsules, and injectables. Among the first steroidal agents was cyproterone acetate, which was patented in the 1960s. Flutamide was the first non-steroidal agent to be approved in the 1980s. Structure and properties A distinction is made between antiandrogens with a steroidal structure (like the … Antiandrogens

Alzheimer’s

Symptoms Alzheimer’s disease manifests itself in a continuously progressive loss of memory and mental and cognitive abilities. Possible symptoms of the disease include: Disorders and loss of memory. Initially, mainly short-term memory is affected (learning new things), later long-term memory is also affected. Forgetfulness, confusion Disorientation Speech, perception and thinking disorders, motor disorders. Personality change, … Alzheimer’s

Mechanism of Action

Most common mechanism of action Most drugs bind to a macromolecular target structure called a drug target. These are usually proteins such as receptors, transporters, channels, and enzymes, or nucleic acids. For example, opioids interact with endogenous opioid receptors to relieve pain. Targets can also be exogenous structures. Penicillins inhibit bacterial enzymes responsible for building … Mechanism of Action

Endothelin Receptor Antagonists

Products Endothelin receptor antagonists are commercially available in the form of film-coated and dispersible tablets. The first agent in this group to be approved was bosentan (Tracleer) in the United States in 2001 and in the EU and Switzerland in 2002. Effects Antivasoconstrictive Reduce pulmonary and systemic vascular resistance Higher blood flow volume without increasing … Endothelin Receptor Antagonists

Angel Trumpets

Products In many countries, no medicines containing preparations of angel’s trumpet are on the market. Angel’s trumpets are sold as ornamental plants. Stem plant Angel’s trumpets belong to the genus and family Solanaceae. Representatives are, for example , and . The decorative plants are originally from South America. They are perennial shrubs or trees with … Angel Trumpets

Orexin Receptor Antagonists

Products Orexin receptor antagonists are commercially available in tablet form. The first agent in this group to be approved in the United States was suvorexant (Belsomra) in 2014. Lemborexant (Dayvigo) followed in 2019. Structure and properties Orexin receptor antagonists are characterized by a central ring structure to which heterocycles are attached on both sides. Effects … Orexin Receptor Antagonists

Antiemetics: Drugs against Nausea or Vomiting

Products Antiemetics are commercially available in the form of tablets, as melting tablets, as solutions (drops), and injectables, among others. They are also administered as suppositories because peroral administration is not possible. In many countries, the best-known antiemetics include domperidone (Motilium, generic) and meclozine, which, along with caffeine and pyridoxine, is contained in Itinerol B6. … Antiemetics: Drugs against Nausea or Vomiting

Antihistamines for Allergies

Products Antihistamines are often taken in the form of tablets. In addition, drops, solutions, lozenges, capsules, gels, creams, eye drops, nasal sprays, and injectable solutions are also available, among others. The first active ingredient from this group was phenbenzamine (Antergan), developed in France in the 1940s. It is no longer commercially available today. Structure and … Antihistamines for Allergies

LAMA

Products LAMAs are commercially available as powders and inhalation solutions and are administered with a specially designed inhaler or with a nebulizer (nebulizer). LAMA is the acronym for , which means long-acting antagonists at muscarinic receptors. Structure and properties LAMAs are derived from the parasympatholytic atropine, which is a natural plant constituent found in various … LAMA

Phytoestrogens

Products Phytoestrogens are commercially available as dietary supplements, for example, in the form of capsules and tablets. They are found in various plants for example in nuts, seeds, fruits and vegetables. A typical example is soy. Structure and properties Phytoestrogens are a structurally disparate group of phytonutrients that resemble estrogens (estradiol) but do not have … Phytoestrogens