Tetracycline: Drug Effects, Side Effects, Dosage and Uses

Products Tetracyclines are commercially available in many countries in the form of tablets, capsules, and injection and infusion solutions, among others. This article refers primarily to peroral therapy. The first tetracycline, chlortetracycline (aureomycin, Lederle), was discovered in the 1940s during screening of soil samples under the direction of Benjamin Minge Duggar and became commercially available … Tetracycline: Drug Effects, Side Effects, Dosage and Uses

Gentian Violet

Products and production Gentian violet solutions are not commercially available as human medicines in many countries and must be prepared for customers in a pharmacy or drugstore. They can also order the solution from specialized suppliers (e.g., Hänseler). According to the New Formulary (NRF), the pure substance methylrosanilinium chloride PhEur should be used (see below), … Gentian Violet

Lumefantrine

Products Lumefantrine is commercially available in tablet form as a fixed combination with artemether (Riamet). It has been approved in many countries since 1999. Structure and properties Lumefantrine (C30H32Cl3NO, Mr = 528.9 g/mol) is a racemate. It exists as a yellow crystalline powder that is insoluble in water. Effects Lumefantrine (ATC P01BF01) has antiparasitic properties. … Lumefantrine

Malachite Green

Products Malachite green is commercially available as a veterinary drug. It is also known as diamond green, basic green 4, CI 42000, bitter almond oil green and Victoria green. Malachite green is not the same as the mineral malachite, a copper hydroxide carbonate. The name is derived from the green color of malachite. Structure and … Malachite Green

Antimalarials

Effects Antiparasitic against plasmodia. Indications Malaria Malaria prophylaxis Also for the treatment of rheumatic diseases, lupus erythematosus. Off-label: some antimalarials such as quinine and chloroquine are used off-label to treat calf cramps. Active ingredients Aminoquinolines: Amodiaquine Chloroquine (Nivaquine, out of commerce). Hydroxychloroquine (Plaquenil) Mepacrine Pamaquin Piperaquine Primaquine Tafenoquin (crinoline) Biguanides: Proguanil (Malarone + Atovaquone). Cycloguanilembonate … Antimalarials

Sarolan

Products Sarolaner was approved in the EU in 2015 and in many countries in 2017 in the form of chewable tablets for dogs (Simparica). Structure and properties Sarolaner (C23H18Cl2F4N2O5S, Mr = 581.4 g/mol) belongs to the isoxazoline group. Effects Sarolaner (ATCvet QP53BX06) has antiparasitic properties against fleas, ticks, and mites. Indications For the treatment of … Sarolan

Imidocarb

Products Imidocarb is commercially available as a solution for injection (Carbesia). It has been approved in many countries since 2011. Structure and properties Imidocarb (C19H20N6O, Mr = 348.4 g/mol) is a substituted carbanilide. It is present in drugs as imidocarbdipropionate. Effects Imidocarb (ATCvet QP51AE01) has antiparasitic properties against ssp. Indications For prevention and treatment of … Imidocarb

Artemether

Products Artemether is commercially available as tablets and dispersible tablets as a fixed combination with lumefantrine (Riamet, some countries: Coartem). It has been approved in many countries since 1999. Structure and properties Artemether (C16H26O5, Mr = 298.4 g/mol) is a methyl ether dervate of the sesquiterpene artemisinin from the annual mugwort (, Qing Hao), a … Artemether

Artesunate

Products No drugs containing artesunate are currently approved in many countries. Structure and properties Artesunate (C19H28O8, Mr = 384.4 g/mol) is a succinyl derivative and a prodrug of dihydroartemisinin. It is derived from artemisinin from annual mugwort (, qing hao), a medicinal plant used in traditional Chinese medicine. Effects Artesunate (ATC P01BE03) has antiparasitic properties … Artesunate

Sweet Wood

Products Licorice is available as cut open or in the form of licorice stems in pharmacies and drugstores. Licorice extract is found in bronchial pastilles, in teas, and various cough medicines, among other products. The extract is also a component of licorice and corresponding confectionery. Stem plant Stem plants include various -species of the legume … Sweet Wood