Gold

Products Gold compounds are commercially available (worldwide) in the form of capsules and injection solutions (e.g., Ridaura, Tauredon), among others. They are rarely used medicinally today. Structure and properties Elemental gold (Latin: aurum, abbreviation: Au, M. r = 96.97 g/mol, atomic number 79) is a chemical element and a lustrous noble metal with a yellow … Gold

Phenylbutazone: Effects, Uses & Risks

Phenylbutazone belongs to the non-steroidal anti-inflammatory drug group. It is used to treat inflammation, pain, and fever. What is phenylbutazone? Phenylbutazone belongs to the non-steroidal anti-inflammatory drug group. It is used to treat inflammation, pain, and fever. The drug phenylbutazone is used both in human medicine and in veterinary medicine. There, based on pyrazolone, an … Phenylbutazone: Effects, Uses & Risks

Mepacrine

Products Mepacrine is no longer commercially available in many countries. At best, mepacrine capsules could be prepared as a magisterial formulation in a well-equipped pharmacy. Alternatively, other antimalarials such as chloroquine or quinine could be used. Structure and properties Mepacrine (C23H30ClN3O, Mr = 399.96 g/mol) is a pale yellow crystalline powder that is soluble in … Mepacrine

Mezlocillin: Effects, Uses & Risks

Mezlocillin is a typical broad-spectrum antibiotic with versatile applications. It finds application in various bacterial infections. What is mezlocillin? Mezlocillin is a ß-lactam antibiotic that belongs to the acylaminopenicillins. Because absorption is poor with oral administration, mezlocillin is administered parenterally-that is, past the intestine. Parenteral administration includes, for example, injection or infusion into a vein … Mezlocillin: Effects, Uses & Risks

Etoricoxib: Effects, Uses & Risks

As a COX-2 inhibitor, etoricoxib belongs to the non-steroidal anti-inflammatory drugs (NSAIDs). The active ingredient, which is used particularly as an anti-inflammatory and pain reliever, is thought to have properties that are gentler on the stomach and intestines than traditional nonsteroidal anti-inflammatory drugs. What is etoricoxib? Etoricoxib is generally applied in tablet form. Etoricoxib (molecular … Etoricoxib: Effects, Uses & Risks

Indomethacin

Definition The drug indomethacin belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). Indomethacin is mainly used to treat rheumatic diseases. Mode of action of Indometacin Indomethacin inhibits the enzyme cyclooxygenase, which inhibits the formation of prostaglandins: Prostaglandins are substances that play a decisive role in the body in mediating pain, fever and inflammation, among … Indomethacin

Side effects | Indomethacin

Side effects The side effects occur mainly with long-term use of indomethacin. These include: Asthmatic complaints (analgesic asthma) due to increased formation of leukotrienes by cyclooxygenase, which cause bronchial constriction Stomach ulcers due to the loss of the mucous membrane protecting effect of prostaglandins Allergic reactions Dizziness, fatigue, nausea, loss of appetite Headaches Contraindications Patients … Side effects | Indomethacin

Lyell Syndrome: Causes, Symptoms & Treatment

Lyell syndrome is a life-threatening acute skin disorder associated with extensive epidermolysis (detachment of the epidermis) due to marked drug intolerance or infection with staphylococci. With an incidence of approximately 1:1,000,000, Lyell syndrome is a rare condition. What is Lyell syndrome? Lyell’s syndrome (also known as “scalded skin syndrome”) is a rare life-threatening acute dermatosis … Lyell Syndrome: Causes, Symptoms & Treatment

Side effects of Methotrexate

Introduction A number of illnesses make it necessary to take methotrexate. Especially if NSAIDs (non-steroidal anti-inflammatory drugs) are not responded to, methotrexate therapy may be indicated. However, methotrexate can also be used to treat active rheumatoid arthritis or severe forms of psoriasis. Methotrexate belongs to the group of active ingredients of specific antirheumatic drugs and … Side effects of Methotrexate

Fertility and pregnancy under methotrexate | Side effects of Methotrexate

Fertility and pregnancy under methotrexate Methotrexate has a teratogenic effect, i.e. it damages the embryo or the “maturing fruit”, if one wants to translate the term literally. Therefore, methotrexate therapy is not possible during pregnancy. It can lead to hereditary damage to the embryo, and in the worst case to abortion. Even after discontinuing methotrexate … Fertility and pregnancy under methotrexate | Side effects of Methotrexate