Definition Thrombocytes are blood platelets, of which each person carries approximately 150,000 to 350,000 per μl of blood. The thrombocytes perform an important function in blood clotting. Platelets therefore ensure that when a patient cuts himself or herself, the wound is closed again as quickly as possible and with as little blood loss as possible … Blood platelets (thrombocytes)
Platelet aggregation When a vessel is injured, the platelets come into contact with the connective tissue, which normally has no contact with the blood. A coagulation factor, the so-called von Willebrand factor (vWF), can now attach itself to this tissue from the blood. The thrombocyte has special receptors for this factor (vWR) and binds to … Platelet aggregation | Blood platelets (thrombocytes)
Blood count In the small blood count the number of thrombocytes is always determined because they have an important function in the coagulation cascade. The thrombocytes can be recognized here as small blood platelets without a cell nucleus. Compared to the white blood cells (leukocytes) and the red blood cells (erythrocytes) they look tiny and … Blood count | Blood platelets (thrombocytes)
Platelet donation In case of injuries or operations where large blood losses occur or in case of people who cannot produce enough platelets due to their disease(s), it may be necessary to administer platelets from other people, as they cannot be produced artificially. Nowadays this is done in the form of platelet concentrates. The donation … Platelet donation | Blood platelets (thrombocytes)
The following drugs are used for thrombosis prophylaxis: Heparin Pentasaccharide Fondaparinux (Arixtra®) Acetylsalicylic acid Oral anticoagulants Thrombin inhibitors Note General information on the topic of thrombosis prophylaxis can be found on the homepage on the topic: Thrombosis prophylaxis Heparins The first large group of anticoagulant drugs for the prevention of thromboembolism are heparins. They are … Drug-induced thrombosis prophylaxis
Pentasaccharide FondaparinuxArixtra® The pentasaccharide fondaparinux (Arixtra®) is a synthetically produced 5-sugar that inhibits factor Xa in the coagulation cascade via antithrombin (a naturally occurring blood clotting inhibitor in the body). The drug is administered by subcutaneous administration (subcutaneously, see c.). Once absorbed into the bloodstream, it binds to antithrombin. The substance is excreted via the … Pentasaccharide FondaparinuxArixtra® | Drug-induced thrombosis prophylaxis
Homeopathic remedies Although homeopathic remedies are not suitable for the sole prophylaxis of thrombosis, they can also help to reduce the risk of thrombosis before and after surgery if the risk factors are low. Suitable remedies include Lachesis, horse chestnut and witch hazel (witch hazel). You can read more information on this topic here: Homeopathy … Homeopathic remedies | Drug-induced thrombosis prophylaxis
Note General information on the topic of thrombosis prophylaxis can be found on the homepage on the topic: Thrombosis prophylaxis Start of prophylaxis The start of thrombosis prophylaxis should be as early as possible to the risk-causing situation. Nowadays, thrombosis prophylaxis is routinely performed in inpatient surgical departments both peri- and postoperatively, usually until discharge. … Start and duration of thrombosis prophylaxis
Primary hemostasis and platelet function The aim of primary hemostasis is to stop bleeding by forming a platelet (thrombus). The platelets are naturally involved in this process, as are a number of different factors (e.g. von Willebrand factor) and receptors. If, for example, a blood vessel is injured, it contracts in the primary reaction (vasoconstriction) … Primary hemostasis and platelet function | Start and duration of thrombosis prophylaxis
Synonyms in a broader sense Thromboembolism prophylaxis Thrombosis protection Thrombosis prevention Thrombosis Blood Clot Embolism Definition and introduction In thrombosis prophylaxis, a distinction is made between physical and medicinal measures. The physical measures include : In drug intervention, a number of different drugs are available to reduce the blood‘s tendency to clot. The points of … Thrombosis prophylaxis
Secondary Hemostasis For permanent closure, the plug must be replaced by a fibrin thrombus. For this purpose, the fibrinogen (or factor I of the blood clotting cascade), which occurs in an inactive precursor in the blood, must be converted to fibrin. This requires a staggered activation of different clotting factors in the blood. This preceding … Secondary Hemostasis | Thrombosis prophylaxis
Synonyms thrombus, blood clot, blood clot Definition A thrombosis is a blood clot that forms in the body’s venous system, closes a blood vessel and prevents venous blood flow to the affected area. Thromboses often occur in the deep veins of the legs and pelvis, less frequently in arm veins. Introduction Thrombi that develop in … Thrombosis in the leg
