Products Dextromethorphan is available in the form of tablets, lozenges, sustained-release capsules, syrup, and drops, among others (in many countries, for example, Bexin, Calmerphan, Calmesin, Pulmofor, combination preparations). The first drugs came on the market in the 1950s. Structure and properties Dextromethorphan (C18H25NO, Mr = 271.4 g/mol) was developed as an analog of codeine and … Dextromethorphan
Products Saxagliptin is commercially available in the form of film-coated tablets (Onglyza). It was approved in many countries after sitagliptin (Januvia) and vildagliptin (Galvus) as the 3rd active ingredient from the gliptins group in February 2010. Since 2012, two additional combination products with metformin have been registered (Duoglyze, Kombiglyze XR). Kombiglyze XR entered the market … Saxagliptin
Symptoms Glaucoma is a progressive eye disease that is initially asymptomatic. Patients have no symptoms until the optic nerve becomes increasingly damaged, which can lead to irreversible visual impairment with visual field loss and blindness. Glaucoma represents the most common cause of blindness. Causes The cause of the disease is usually an increase in intraocular … Glaucoma: Causes and Treatment
Products In many countries, drugs containing butalbital are no longer approved (e.g., Cafergot-PB). Combination products are still on the market in some countries, including the United States, where numerous products are available. Structure and properties Butalbital (C11H16N2O3, Mr = 224.3 g/mol) or 5-allyl-5-isobutylbarbituric acid exists as a slightly bitter, white, odorless, crystalline powder that is … Butalbital
Products Gliptins are commercially available in the form of film-coated tablets. Sitagliptin (Januvia) was the first representative to be approved in the United States in 2006. Today, various active ingredients and combination products are commercially available (see below). They are also called dipeptidyl peptidase-4 inhibitors. Structure and properties Some gliptins have a proline-like structure because … Gliptine
Products Noscapine is commercially available in the form of lozenges, capsules, drops, as a syrup, and as suppositories. Except for Tussanil N, the drugs are combination products. Structure and properties The phthalideisoquinoline noscapine (C22H23NO7, Mr = 413.4 g/mol) is present in drugs as a free base or as noscapine hydrochloride monohydrate. Noscapine is a white … Noscapine
Products Kanamycin is marketed in many countries exclusively as a veterinary drug and in combination preparations in the form of a suspension (Kanamastine, Ubrolexin). It has been approved since 1989. In other countries, kanamycin eye drops and ointments are available for human use. Structure and properties Kanamycin is present in drugs as kanamycin monosulfate (C18H38N4O15S … Kanamycin
Definition Dual medication is when a patient under a doctor’s care is inadvertently given two medications with the same active ingredient. It is also possible for the patient to purchase medications as part of self-medication that result in a dual medication. Examples For example, duplicate prescribing can occur when a patient receives a new generic … Dual Medication
Products Aliskiren is commercially available in the form of film-coated tablets (Rasilez, Rasilez HCT + hydrochlorothiazide). It was approved in many countries, in the EU and in the United States in 2007 (Other brand name: Tekturna). Note: Other combination preparations, e.g., with amlodpine (Rasilamlo), are no longer available. Structure and properties Aliskiren (C30H53N3O6, Mr = … Aliskiren
Products Menotropin is commercially available as an injectable (Menopur, Merional HG, combination products). It has been used medicinally since the 1960s. Structure and properties Menotropin is a highly purified human menopausal gonadotropin (hMG, ) derived from human urine of postmenopausal women. Argentina and China are reported as the countries of origin. Menotropin is a mixture … Menotropin
Products Rifampicin is commercially available as film-coated tablets, coated tablets, capsules, and injectables (Rimactan, generics). In addition to mono, various combination preparations are also available. Rifampicin has been approved in many countries since 1968. This article refers to peroral monotherapy. Structure and properties Rifampicin (C43H58N4O12, Mr = 823 g/mol) exists as a reddish brown to … Rifampicin
Products Pyrazinamide is commercially available in tablet form (Pyrazinamide Labatec, combination products). It was first used in the 1950s for the treatment of tuberculosis. Structure and properties Pyrazinamide (C5H5N3O, Mr = 123.1 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is a 1,4-pyrazine and an amide. Pyrazinamide is an … Pyrazinamide
