Products Imipramine was commercially available in the form of dragées (Tofranil). It was developed at Geigy in Basel. Its antidepressant properties were discovered in the 1950s by Roland Kuhn at the psychiatric clinic in Münsterlingen (Thurgau). It was approved in many countries in 1958 as the first active ingredient in the tricyclic antidepressant group. In … Imipramine: Drug Effects, Side Effects, Dosage and Uses
Products Binimetinib was approved in the EU and US in 2018 and in many countries in 2019 in film-coated tablet form (Mektovi). Structure and properties Binimetinib (C17H15BrF2N4O3, Mr = 441.2 g/mol) exists as a light yellow powder that is practically insoluble in water. Effects Binimetinib (ATC L01XE41) has antitumor and antiproliferative properties. The effects are … Binimetinib
Products Norfloxacin is commercially available in the form of film-coated tablets. It was approved in many countries in 1983. The original product, Noroxin, is no longer available, but generics are available. Structure and properties Norfloxacin (C16H18FN3O3, 319.33 g/mol) is a fluoroquinolone. It exists as a white to pale yellow, hygroscopic, photosensitive crystalline powder that is … Norfloxacin
Products Roflumilast is commercially available in the form of film-coated tablets (Daxas). The drug was approved in many countries in 2011. Structure and properties Roflumilast (C17H14Cl2F2N2O3, Mr = 403.2 g/mol) has a nonsteroidal benzamide structure and is unrelated to the glucocorticoids. It exists as a white powder that is practically insoluble in water. Effects Roflumilast … Roflumilast
Products Theophylline is commercially available as sustained-release tablets and as an injectable (Unifyl, Aminophylline). It has been approved in many countries since 1954. Euphylline is no longer marketed. Structure and properties Theophylline (C7H8N4O2, Mr = 180.2 g/mol) is a white crystalline powder that is sparingly soluble in water. It is a methylxanthine and structurally related … Theophylline: Drug Effects, Side Effects, Dosage and Uses
Products Pomalidomide is commercially available in the form of hard capsules (Imnovid). It has been approved in many countries since 2014. It has been registered in the EU and the United States since 2013. Structure and properties Pomalidomide (C13H11N3O4, Mr = 273.2 g/mol) is an amino derivative of thalidomide and a racemate. It is also … Pomalidomide
