Pioglitazone

Products Pioglitazone is commercially available in tablet form (Actos, generics). It is also available as a fixed-dose combination with metformin (Competact). Pioglitazone has been approved in many countries since 2000. Structure and properties Pioglitazone (C19H20N2O3S, Mr = 356.4 g/mol) belongs to the thiazolidinediones. It is present in drugs as a racemate and as pioglitazone hydrochloride, … Pioglitazone

Montelukast

Products Montelukast is commercially available as film-coated tablets and as granules and chewable tablets for children (Singulair, generic). It has been approved in many countries since 1998. Structure and properties Montelukast (C35H36ClNO3S, Mr = 586.18 g/mol) is a chloroquinoline derivative. It is present in drugs as montelukast sodium, a white crystalline powder that is readily … Montelukast

Tucatinib

Products Tucatinib was approved in the United States and many countries in 2020 in film-coated tablet form (Tukysa). Structure and properties Tucatinib (C26H24N8O2, Mr = 480.5 g/mol) Effects Tucatinib has antitumor and antiproliferative properties. The effects are due to inhibition of HER2 tyrosine kinase. The half-life is approximately 8.5 hours. Indications In combination with trastuzumab … Tucatinib