Products Antihistamines are often taken in the form of tablets. In addition, drops, solutions, lozenges, capsules, gels, creams, eye drops, nasal sprays, and injectable solutions are also available, among others. The first active ingredient from this group was phenbenzamine (Antergan), developed in France in the 1940s. It is no longer commercially available today. Structure and … Antihistamines for Allergies
Effects Appetite stimulant Indications Loss of appetite Active ingredients By cause: herbal bitter agents and spices: E.g. wormwood, ginger, take half an hour before meals. Prokinetics: Metoclopramide (Paspertin). Domperidone (Motilium) Antihistamines and anticholinergics: Pizotifen (Mosegor, out of commerce), cyproheptadine (out of commerce in many countries). Antidepressants: E.g. mirtazapine, caution: some antidepressants such as the SSRIs … Appetite Stimulants
Products Loratadine is commercially available in tablet form (Claritine, Claritine Pollen, generics). It has been approved in many countries since 1991. The active metabolite desloratadine is also available (Aerius, generics). Structure and properties Loratadine (C22H23ClN2O2, Mr = 382.9 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug … Loratadine
Products Cyproheptadine is no longer commercially available in many countries (formerly Periactin). In the United States, it is available in tablet, syrup, and powder forms, among others. Structure and properties Cyproheptadine (C21H21N, Mr = 287.4 g/mol) is a methylpiperidine derivative structurally related to pizotifen (Mosegor, off label). It is present in drugs as cyproheptadine hydrochloride, … Cyproheptadine
Background Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter biosynthesized from the amino acid tryptophan by decarboxylation and hydroxylation. It binds to seven different families of the serotonin receptor (5-HT1 to 5-HT7) and elicits central and peripheral effects that affect mood, behavior, sleep-wake cycle, thermoregulation, pain perception, appetite, vomiting, muscles, and nerves, among others. Serotonin is vasoconstrictive … Serotonin Syndrome: Causes and Treatment
